USUARIOS REGISTRADOS
Ingrese con su correo institucional
Ingrese con su correo institucional
Unidad de Investigación
ID: 741
INSTITUTO CLODOMIRO PICADO
Mostrando 13 personas investigadoras
| NOMBRE |
|
CORREO ELECTRÓNICO |
|---|---|---|
| Aguilar Ulloa, Wendy Maria | Activo | maaguw@gmail.com |
| Altamirano Monge, Jose | Inactivo | |
| Arce Estrada, Denice | Inactivo | |
| Arias Rodríguez, Jazmín Melania | Inactivo | jazz.cr@hotmail.com |
| Bonilla Murillo, Fabián | Activo | fabian.bonilla@ucr.ac.cr |
| Boroschek Kraoskopf, Ruben | Inactivo | |
| Calvete Chornet, Juan José | Inactivo | jcalvete@ibv.csic.es |
| Camacho Umaña, Ericka | Activo | erika.camachoumana@ucr.ac.cr |
| Castro Castro, Ana Cristina | Inactivo | anacristinacastro@gmail.com |
| Chaves Araya, Stephanie | Activo | |
| Chaves Araya, Stephanie | Activo | stephanie.chavesaraya@ucr.ac.cr |
| Escalante Muñoz, Teresa | Activo | teresa.escalante@ucr.ac.cr |
| Estrada Umaña, Ricardo | Inactivo | ricardoe1957@hotmail.com |
Mostrando 76 personal colaborador
Mostrando 20 proyectos
Mostrando 8 proyectos en colaboración
Mostrando 578 publicaciones
| TÍTULO | TIPO | AUTOR | PROYECTOS | FECHA |
|---|---|---|---|---|
| Desarrollo de las universidades públicas de Latinoamérica: una visión alternativa al modelo economicista de rentabilidad |
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No disponible |
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| La investigación en la Universidad de Costa Rica: situación actual y perspectivas |
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No disponible |
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| Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920) |
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2019 | |
| Novel three-finger toxins from Micrurus dumerilii and Micrurus mipartitus coral snake venoms: phylogenetic relationships and characterization of Clarkitoxin-I-Mdum |
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2019 | |
| Three-finger toxins from the venom of Micrurus tschudii (desert coral snake): isolation and characterization of tschuditoxin-I |
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2019 | |
| Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species |
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2019 | |
| Caracterización proteómica, funcional e inmunoneutralización del veneno de la serpiente Porthidium porrasi de Costa Rica |
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No disponible |
2019 |
| Venom characterization of the bark scorpion Centruroides edwardsii (Gervais 1843): composition, biochemical activities and in vivo toxicity for potential prey |
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2019 | |
| Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro |
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2019 | |
| Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric β-neurotoxin |
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No disponible |
2019 |
| Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: comparative characterization and synergism between Asp49 and Lys49 variants |
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2019 | |
| Reflexiones desde la academia. Universidad, ciencia y sociedad |
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No disponible |
2019 |
| First look into the venom of Roatan Island´s critically endangered coral snake Micrurus ruatanus: proteomic characterization, toxicity, immunorecognition and neutralization by an antivenom |
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2019 | |
| Enzymatic labelling of venom phospholipase A2 toxins |
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No disponible |
2019 |
| Proteomic profiling, functional characterization, and immunoneutralization of the venom of Porthidium porrasi, a pitviper endemic to Costa Rica |
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2019 | |
| Neutralizing properties of Varespladib toward group I and II myotoxic phospholipases A2 |
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2019 | |
| A secreted phospholipase A2 induces formation of smooth muscle foam cells which trans-differentiate to macrophage-like state |
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No disponible |
2019 |
| New insights into the phylogeographic distribution of the 3FTx/PLA2 venom dichotomy across genus Micrurus in South America |
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2019 | |
| Cloning, purification and characterization of nigrelysin, a novel actinoporin from the sea anemone Anthopleura nigrescens |
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No disponible |
2019 |
| In vivo neutralization of the dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG monoclonal antibodies |
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No disponible |
2018 |
| Nociones de Inmunologia |
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No disponible |
2018 |
| Cannibalism by large tadpoles of Rhinophrynus dorsalis (Anura: Rhinophrynidae) |
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No disponible |
2018 |
| Biological and proteolytic variation in the venom of Crotalus scutulatus scutulatus from Mexico |
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No disponible |
2018 |
| Innovative immunization strategies for antivenom development |
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No disponible |
2018 |
| A myotoxic Lys49 phospholipase A2-homologue is the major component of the venom of Bothrops cotiara from Misiones, Argentina |
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2018 | |
| Pros and cons of different therapeutic antibody formats for recombinant antivenom development |
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No disponible |
2018 |
| Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus |
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2018 | |
| Delayed oral LY333013 rescues mice from highly neurotoxic, lethal doses of Papuan Taipan (Oxyuranus scutellatus) venom |
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No disponible |
2018 |
| MipLAAO, a new L-amino acid oxidase from the redtail coral snake, Micrurus mipartitus |
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2018 | |
| Intravascular hemolysis induced by phospholipases A2 from the venom of the Eastern coral snake, Micrurus fulvius: functional profile of hemolytic and non-hemolytic isoforms |
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2018 | |
| A snake venom secreted phospholipase A2 induces foam cell formation depending on the activation of factors involved in lipid homeostasis |
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No disponible |
2018 |
| Prolonged development of the middle ear in Rhinella horribilis |
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No disponible |
2018 |
| Depletion of complement enhances the clearance of Brucella abortus in mice |
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2018 | |
| Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity |
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2018 | |
| Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms |
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No disponible |
2018 |
| A novel pentameric phospholipase A2 myotoxin (PophPLA2) from the venom of the pit viper Porthidium ophryomegas |
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2018 | |
| Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles) |
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2017 | |
| Exploring the venom of the forest cobra snake: Toxicovenomics and antivenom profiling of Naja melanoleuca |
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No disponible |
2017 |
| Primary structures and partial toxicological characterization of two phospholipases A2 from Micrurus mipartitus and Micrurus dumerilii coral snake venoms |
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2017 | |
| Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping |
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No disponible |
2017 |
| Detection of a synthetic sex steroid in the American crocodile (Crocodylus acutus): Evidence for a novel environmental androgen |
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2017 | |
| Screening for target toxins of the antiophidic protein DM64 through a gel-based interactomics approach |
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No disponible |
2017 |
| Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster” |
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No disponible |
2017 |
| Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis) |
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No disponible |
2017 |
| Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom |
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No disponible |
2017 |
| Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect |
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No disponible |
2017 |
| Pitfalls to avoid when using phage display for snake toxins |
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No disponible |
2017 |
| High-density peptide microarray exploration of the antibody response in a rabbit immunized with a neurotoxic venom fraction |
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No disponible |
2017 |
| Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms |
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No disponible |
2017 |
| Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead |
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No disponible |
2017 |
| Proteoform-resolved quantitative venomics: looking through a crystal ball |
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No disponible |
2017 |
| Exploration of immunoglobulin transcriptomes from mice immunized with three-finger toxins and phospholipases A2 from the Central American coral snake, Micrurus nigrocinctus |
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No disponible |
2017 |
| Physicochemical characterization of Jicaro seeds (Crescentia alata H.B.K.): a novel protein-rich and oleaginous seed |
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No disponible |
2017 |
| Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: A biochemical and immunohistochemical study |
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No disponible |
2016 |
| Venom of the Coral Snake Micrurus clarki: Proteomic Profile, Toxicity, Immunological Cross-Neutralization, and Characterization of a Three-Finger Toxin |
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No disponible |
2016 |
| Mecanismo de açao dos venenos de cobras corais |
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No disponible |
2016 |
| Actividad letal de seis venenos de serpientes de importancia médica en el Ecuador |
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No disponible |
2016 |
| Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: proteome, toxicity, and cross-neutralization by antivenom |
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2016 | |
| Preclinical evaluation of three polyspecific antivenoms against the venom of Echis ocellatus: Neutralization of toxic activities and antivenomics |
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No disponible |
2016 |
| The need for an integrated approach in confronting snakebite envenoming in Latin America: the relevance of endogenous scientific and technological research |
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No disponible |
2016 |
| Metaloproteinasas dependientes de Zinc: Protagonistas centrales en la Fisiopatología de Envenenamientos por Serpientes de la familia Viperidae |
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No disponible |
2016 |
| Hydrology Affects Environmental and Spatial Structuring of Microalgal Metacommunities in Tropical Pacific Coast Wetlands |
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2016 | |
| Divergent functional profiles of acidic and basic phospholipases A2 in the venom of the snake Porthidium lansbergii lansbergii |
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2016 | |
| Desarrollo de la herpetocultura en Costa Rica: Situación actual de herpetarios y manejo ex situ de reptiles y anfibios |
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No disponible |
2016 |
| From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy |
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No disponible |
2016 |
| Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice |
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No disponible |
2016 |
| N-terminal peptide of myotoxin II from Bothrops asper venom enhances the activity of endothelin converting enzyme and neprilysin |
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No disponible |
2016 |
| Regional warming and the thermal regimes of American crocodile nests in the Tempisque Basin, Costa Rica |
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No disponible |
2016 |
| Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains |
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No disponible |
2016 |
| Novel catalytically-inactive PII metalloproteinases from a viperid snake venom with substitutions in the canonical zinc-binding motif |
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2016 | |
| Larval aggression is independent of food limitation in nurseries of a poison frog |
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No disponible |
2016 |
| Venomic analysis of the poorly studied desert coral snake, Micrurus tschudii tschudii, supports the 3FTx/PLA2 dichotomy across Micrurus venoms |
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No disponible |
2016 |
| Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab0)2 and whole IgG antivenoms |
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No disponible |
2016 |
| Understanding and confronting snakebite envenoming: The harvest of cooperation |
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No disponible |
2016 |
| Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis |
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No disponible |
2016 |
| Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the Brazilian Atlantic rainforest |
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No disponible |
2016 |
| High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays |
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No disponible |
2016 |
| Methyltestosterone alters sex determination in the American alligator (Alligator mississippiensis) |
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No disponible |
2016 |
| Bacterial Sphingomyelinases and Phospholipases as Virulence Factors |
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2016 | |
| Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii |
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No disponible |
2016 |
| Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding |
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No disponible |
2016 |
| Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2 |
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No disponible |
2016 |
| Toxicovenomics and antivenom profiling of the Eastern green mamba snake (Dendroaspis angusticeps). |
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No disponible |
2016 |
| Venoms of Micrurus coral snakes: evolutionary trends in compositional patterns emerging from proteomic analyses |
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2016 | |
| Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom |
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No disponible |
2016 |
| A cryptic palm-pitviper species (Squamata: Viperidae: Bothriechis) from the Costa Rican highlands, with notes on the variation within B. nigroviridis |
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No disponible |
2016 |
| Brucella canis Is an Intracellular Pathogen That Induces a Lower Proinflammatory Response than Smooth Zoonotic Counterparts |
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2015 | |
| Minipool Caprylic Acid Fractionation of Plasma Using Disposable Equipment: A Practical Method to Enhance Immunoglobulin Supply in Developing Countries |
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No disponible |
2015 |
| MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity |
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No disponible |
2015 |
| A bright future for integrative venomics |
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No disponible |
2015 |
| Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage |
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No disponible |
2015 |
| Phospholipases a2 from Viperidae snakes: Differences in membranotropic activity between enzymatically active toxin and its inactive isoforms |
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No disponible |
2015 |
| Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids |
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No disponible |
2015 |
| Snake venomics of monocled cobra (Naja kaouthia) and investigation of human IgG response against venom toxins |
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No disponible |
2015 |
| Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis |
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No disponible |
2015 |
| A Call for Incorporating Social Research in the Global Struggle against Snakebite |
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No disponible |
2015 |
| Multiple paths to aquatic specialisation in four species of Central American Anolis lizards |
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No disponible |
2015 |
| Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score |
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No disponible |
2015 |
| First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis |
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2015 | |
| Seasonal wetlands in the Pacific coast of Costa Rica and Nicaragua: environmental characterisation and conservation status |
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2015 | |
| Effect of geographical variation of Echis ocellatus, Naja nigricollis and Bitis arietans venoms on their neutralization by homologous and heterologous antivenoms |
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No disponible |
2015 |
| Membrane-damaging and cytotoxic sphingomyelinases and phospholipases |
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No disponible |
2015 |
| Group-II phospholipase A2 enzymes |
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No disponible |
2015 |
| Purification of equine whole IgG snake antivenom by using an aqueous two phase system as a primary purification step |
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2015 | |
| A constant area monolayer method to assess optimal lipid packing for lipolysis tested with several secreted phospholipases A2 |
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2015 | |
| Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: identification of key toxin targets for antivenom development. |
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No disponible |
2015 |
| Extracts of Renealmia alpinia (Rottb.) MAAS Protect against Lethality and Systemic Hemorrhage Induced by Bothrops asper Venom: Insights from a Model with Extract Administration before Venom Injection |
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No disponible |
2015 |
| Venomics and antivenomics of Bothrops erythromelas from five geographic populations within the Caatinga ecoregion of northeastern Brazil |
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No disponible |
2015 |
| Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide |
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No disponible |
2015 |
| Antivenomics: a proteomics tool for studying the immunoreactivity of antivenoms |
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2015 | |
| Proteomic and functional analysis of the venom of Porthidium lansbergii lansbergii (Lansberg’s hognose viper) from the Atlantic Department of Colombia |
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No disponible |
2015 |
| Improved biomass and protein production in solid-state cultures of an Aspergillus sojae strain harboring the Vitreoscilla hemoglobin |
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No disponible |
2015 |
| Lachesis stenophrys venom reduces the equine antibody response towards Bothrops asper venom used as co-immunogen in the production of polyspecific snake antivenom |
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2015 | |
| The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay |
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2015 | |
| Snakebites are associated with poverty, weather fluctuations, and El Niño |
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No disponible |
2015 |
| Evaluation of the preclinical efficacy of four antivenoms, distributed in sub-Saharan Africa, to neutralize the venom of the carpet viper, Echis ocellatus, from Mali, Cameroon, and Nigeria |
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No disponible |
2015 |
| Phospholipase A2 enhances the endothelial cell detachment effect of a snake venom metalloproteinase in the absence of catalysis |
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2015 | |
| Assessing endotoxins in equine-derived snake antivenoms: Comparison of the USP pyrogen test and the Limulus Amoebocyte Lysate assay (LAL) |
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2015 | |
| Índices bibliométricos y revistas de ‘corriente central’: implicaciones para el desarrollo de las ciencias naturales en Costa Rica |
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No disponible |
2015 |
| Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus |
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No disponible |
2014 |
| Intravascular hemolysis induced by the venom of the Eastern coral snake, Micrurus fulvius, in a mouse model: Identification of directly hemolytic phospholipases A2 |
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No disponible |
2014 |
| Immunological profile of antivenoms: preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays |
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No disponible |
2014 |
| Critical role of TLR2 and MyD88 for functional response of macrophages to a group IIA-Secreted phospholipase A2 from snake venom |
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No disponible |
2014 |
| The analgesics morphine and tramadol do not alter the acute toxicity induced by Bothrops asper snake venom in mice |
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No disponible |
2014 |
| An Asp49 Phospholipase A2 from Snake Venom Induces Cyclooxygenase-2 Expression and Prostaglandin E2 Production via Activation of NF-κB, p38MAPK, and PKC in Macrophages |
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No disponible |
2014 |
| Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms |
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No disponible |
2014 |
| Tissue Damage and Inflammation Induced by Snake Venoms |
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No disponible |
2014 |
| Proteomic and toxicological profiling of the venom of Bothrocophias campbelli, a pitviper species from Ecuador and Colombia |
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2014 | |
| Understanding structural and functional aspects of PII snake venom metalloproteinases: Characterization of BlatH1, a hemorrhagic dimeric enzyme from the venom of Bothriechis lateralis |
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No disponible |
2014 |
| Utilidad de los péptidos sintéticos en estudios de estructura-función e identificación de epitopos en toxinas |
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No disponible |
2014 |
| Venomous snakes of Costa Rica: biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics |
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2014 | |
| Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead |
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No disponible |
2014 |
| Comparison of the adjuvant activity of aluminum hydroxide and calcium phosphate on the antibody response towards Bothrops asper snake venom |
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No disponible |
2014 |
| Industrial Production and Quality Control of Snake Antivenoms |
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No disponible |
2014 |
| Current challenges for confronting the public health problem of snakebite envenoming in Central America |
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No disponible |
2014 |
| Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: An antivenomics and neutralization study |
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2014 | |
| Effect of the metalloproteinase inhibitor batimastat in the systemic toxicity induced by Bothrops asper snake venom: understanding the role of metalloproteinases in envenomation |
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2014 | |
| Snakebite Envenomingin Latin America and the Caribbean |
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No disponible |
2014 |
| Anticomplementary Activity of Horse IgG and F(ab’)2 Antivenoms |
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No disponible |
2014 |
| Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: Comparison of their stability in an accelerated test |
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No disponible |
2014 |
| Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo |
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2014 | |
| Snake venomics of Bothrops punctatus, a semi-arboreal pitviper species from Antioquia, Colombia |
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No disponible |
2014 |
| Venomics of new world pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon |
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2014 | |
| A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms |
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No disponible |
2014 |
| A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming |
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No disponible |
2014 |
| Epidemiology of rapes in Costa Rica: Characterization of victims, perpetrators and circumstances surrounding forced intercourse |
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No disponible |
2014 |
| Two color morphs of the pelagic yellow-bellied sea snake, pelamis platura, from different locations of Costa Rica: snake venomics, toxicity, and neutralization by antivenom |
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2014 | |
| Antivenomic Characterization of Two Antivenoms Against the Venom of the Taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia |
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No disponible |
2014 |
| Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka |
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2014 | |
| Proteomic and functional profiling of the venom of Bothrops ayerbei from Cauca, Colombia, reveals striking interspecific variation with Bothrops asper venom |
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2014 | |
| Evidence of maternal provisioning of alkaloid-based chemical defenses in the strawberry poison frog Oophaga pumilio |
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No disponible |
2014 |
| Role of enzymatic activity inmuscle damage and cytotoxicity induced by Bothrops asper Asp49 phospholipase A2 myotoxins: are there additional effector mechanisms involved? |
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No disponible |
2014 |
| A neutralizing recombinant single chain antibody, scFv, against BaP1, A P-I hemorrhagic metalloproteinase from Bothrops asper snake venom |
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No disponible |
2014 |
| Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica |
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No disponible |
2014 |
| Role of the animal model on the pharmacokinetics of equine-derived antivenoms |
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No disponible |
2013 |
| Amino acid sequence and biological characterization of BlatPLA2, a non-toxic acidic phospholipase A2 from the venom of the arboreal snake Bothriechis lateralis from Costa Rica |
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2013 | |
| Snake venomics of Lachesis muta rhombeata and genus-wide antivenomics assessment of the paraspecific immunoreactivity of two antivenoms evidence the high compositional and immunological conservation across Lachesis |
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No disponible |
2013 |
| Polyspecific Antivenom Liquid |
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No disponible |
2013 |
| Suero antiofidico polivalente |
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No disponible |
2013 |
| Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus |
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No disponible |
2013 |
| A catalytically-inactive snake venom Lys49 phospholipase A2 homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages |
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No disponible |
2013 |
| Tratamiento hospitalario del envenenamiento por mordedura de serpiente |
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No disponible |
2013 |
| Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins – distinct mechanisms of action |
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No disponible |
2013 |
| Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture |
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No disponible |
2013 |
| Comparison of venom composition and biological activities of the subspecies Crotalus lepidus lepidus, Crotalus lepidus klauberi and Crotalus lepidus morulus from Mexico |
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No disponible |
2013 |
| Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies |
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No disponible |
2013 |
| New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India |
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No disponible |
2013 |
| Proteomic analysis of Bothrops pirajai snake venom and characterization of BpirMP, a new P-I metalloproteinase |
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No disponible |
2013 |
| Algoritmo para el diagnóstico y tratamiento con antivenenos en pacientes mordidos por serpientes en Centroamérica |
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No disponible |
2013 |
| Antivenom for snakebite envenoming in Sri Lanka: The need for geographically specific antivenom and improved efficacy |
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No disponible |
2013 |
| A Lys49 Phospholipase A2, Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region |
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No disponible |
2013 |
| Phospholipases A2: Unveiling the secrets of a functionally versatile group of snake venom toxins |
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No disponible |
2013 |
| Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model |
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No disponible |
2013 |
| Preclinical assessment of a polyspecific antivenom against the venoms of Cerrophidion sasai, Porthidium nasutum and Porthidium ophryomegas: Insights from combined antivenomics and neutralization assays |
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No disponible |
2013 |
| Using Geographical Information Systems to Identify Populations in Need of Improved Accessibility to Antivenom Treatment for Snakebite Envenoming in Costa Rica |
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No disponible |
2013 |
| Suero antiofídico anti-coral |
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No disponible |
2013 |
| Generalidades de serpientes venenosas en Costa Rica |
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No disponible |
2013 |
| The Need for Full Integration of Snakebite Envenoming within a Global Strategy to Combat the Neglected Tropical Diseases: The Way Forward |
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No disponible |
2013 |
| Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics |
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No disponible |
2013 |
| Biochemical and biological characterization of two serine proteinases from Colombian Crotalus durissus cumanensis snake venom |
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No disponible |
2013 |
| Guía de información: Serpientes de Costa Rica y prevención de mordeduras |
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No disponible |
2013 |
| Instituto Clodomiro Picado |
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No disponible |
2013 |
| Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms |
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No disponible |
2013 |
| Why myotoxin-containing snake venoms possess powerful nucleotidases? |
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No disponible |
2013 |
| Efficacy of IgG and F(ab′)2 Antivenoms to Neutralize Snake Venom-induced Local Tissue Damage as Assessed by the Proteomic Analysis of Wound Exudate |
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2012 | |
| Identification of linear B-cell epitopes on myotoxin-II, a Lys49 phospholipase A2 homologue from Bothrops asper snake venom |
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2012 | |
| To beg or to freeze: multimodal sensory integration directs behavior in a tadpole |
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No disponible |
2012 |
| Envenomations by Bothrops and Crotalus Snakes Induce the Release of Mitochondrial Alarmins |
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No disponible |
2012 |
| Snake venom Lys49 myotoxins: from phospholipases A2 to non-enzymatic membrane disruptors |
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2012 | |
| Investigación científica y tecnológica en el Instituto Clodomiro Picado: Una perspectiva bibliométrica de cuatro décadas (1970-2010) |
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No disponible |
2012 |
| A Lys49-PLA2 myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling |
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No disponible |
2012 |
| Identification of New Snake Venom Metalloproteinase Inhibitors Using Compound Screening and Rational Peptide Design |
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No disponible |
2012 |
| Venenos de serpiente: de la investigación al tratamiento |
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No disponible |
2012 |
| Venom of Bothrops asper from Mexico and Costa Rica: Intraspecific variation and cross-neutralization by antivenoms |
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2012 | |
| Low pH formulation of whole IgG antivenom: Impact on quality, safety, neutralizing potency and viral inactivation |
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No disponible |
2012 |
| Snake venomics of the pit vipers Porthidium nasutum, Porthidium ophryomegas, and Cerrophidion godmani from Costa Rica: Toxicological and taxonomical insights |
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No disponible |
2012 |
| An acidic phospholipase A2 with antibacterial activity from Porthidium nasutum snake venom |
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No disponible |
2012 |
| Isolation and biochemical, functional and structural characterization of a novel L-amino acid oxidase from Lachesis muta snake venom |
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No disponible |
2012 |
| Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: Keys to understand the variable immune response in horses |
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No disponible |
2012 |
| Snake venomics and toxicological profiling of the arboreal pitviper Bothriechis supraciliaris from Costa Rica |
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No disponible |
2012 |
| Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab0)2] antivenoms, in Bothrops asper bites in Colombia |
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No disponible |
2012 |
| Antiplasmodial effect of the venom of Crotalus durissus cumanensis, crotoxin complex and Crotoxin B |
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No disponible |
2012 |
| Inversión en ciencia, tecnología e innovación: proyectando a Costa Rica |
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No disponible |
2012 |
| La situación de los antivenenos liofilizados en América Latina: Aspectos tecnológicos y de salud pública |
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No disponible |
2012 |
| Second generation snake antivenomics: Comparing immunoaffinity and immunodepletion protocols |
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No disponible |
2012 |
| Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in venom toxicity |
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No disponible |
2012 |
| Purification of IgG and albumin from human plasma by aqueous two phase system fractionation |
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No disponible |
2012 |
| Snake venomics of crotalus tigris: the minimalist toxin arsenal of the deadliest neartic rattlesnake venom: evolutionary clues for generating a pan-specific antivenom against crotalid type II venoms |
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No disponible |
2012 |
| Implementación de un laboratorio de análisis proteómicos en el Instituto Clodomiro Picado (UCR): primeras experiencias en Costa Rica |
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No disponible |
2012 |
| Improving antivenom availability and accessibility: Science, technology, and beyond |
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No disponible |
2012 |
| Resurrexit, sicut dixit, alleluia. Snake venomics from a 26-years old polyacrylamide focusing gel |
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No disponible |
2012 |
| Mipartoxin-I, a novel three-finger toxin, is the major neurotoxic component in the venom of the redtail coral snake Micrurus mipartitus (Elapidae) |
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2012 | |
| A group IIA-secreted phospholipase A2 from snake venom induces lipid body formation in macrophages: the roles of intracellular phospholipases A2 and distinct signaling pathways |
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No disponible |
2011 |
| Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management |
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No disponible |
2011 |
| Role of collagens and perlecan in microvascular stability: exploring the mechanism of capillary vessel damage by snake venom metalloproteinases |
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No disponible |
2011 |
| Immune Response Towards Snake Venoms |
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2011 | |
| Antivenoms for Snakebite Envenomings |
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No disponible |
2011 |
| Venenos de serpientes de la familia Viperidae en América: Bioquímica y fisiopatología. |
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No disponible |
2011 |
| Comparison of the effect of Crotalus simus and Crotalus durissus ruruima venoms on the equine antibody response towards Bothrops asper venom: Implications for the production of polyspecific snake antivenoms |
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2011 | |
| Poor regenerative outcome after skeletal muscle necrosis induced by Bothrops asper venom: alterations in microvasculature and nerves |
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2011 | |
| A phospholipase A2 from Bothrops asper snake venom activates neutrophils in culture: Expression of cyclooxygenase-2 and PGE2 biosynthesis |
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No disponible |
2011 |
| Proteomics of Wound Exudate in Snake Venom-Induced Pathology: Search for Biomarkers To Assess Tissue Damage and Therapeutic Success |
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No disponible |
2011 |
| Key events in microvascular damage induced by snake venom hemorrhagic metalloproteinases |
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2011 | |
| Envenenamientos por mordeduras de serpientes en América Latina y el Caribe: Una visión integral de carácter regional |
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No disponible |
2011 |
| Comparative study of the cytolytic activity of snake venoms from African spitting cobras (Naja spp., Elapidae) and its neutralization by a polyspecific antivenom |
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2011 | |
| Snake Venomics of African Spitting Cobras: Toxin Composition and Assessment of Congeneric Cross-Reactivity of the Pan-African EchiTAb-Plus-ICP Antivenom by Antivenomics and Neutralization Approaches |
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2011 | |
| Membrane cholesterol modulates the cytolytic mechanism of myotoxin II, a Lys49 phospholipase A2 homologue from the venom of Bothrops asper |
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No disponible |
2011 |
| Venomic and antivenomic analyses of the Central American coral snake, Micrurus nigrocinctus (Elapidae) |
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No disponible |
2011 |
| Proteomic and biological characterization of the venom of the redtail coral snake, Micrurus mipartitus (Elapidae), from Colombia and Costa Rica |
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2011 | |
| Phospholipases A2 From Viperidae Snake Venoms: How do They Induce Skeletal Muscle Damage? |
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No disponible |
2011 |
| Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing |
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No disponible |
2011 |
| Preclinical evaluation of caprylic-acid fractionated IgG antivenom for the treatment of taipan (Oxyuranus scutellatus) envneoming in Papua New Guinea |
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No disponible |
2011 |
| Ending the drought: New strategies for improving the flow of affordable, effective antivenoms in Asia and Africa |
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No disponible |
2011 |
| Differences in escape behavior between a cryptic and an aposematic litter frog |
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No disponible |
2011 |
| High resolution analysis of snake venom metalloproteinase (SVMP) peptide bond cleavage specificity using proteome based peptide libraries and mass spectrometry |
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No disponible |
2011 |
| Antivenoms for the treatment of snakebite envenomings: The road ahead |
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No disponible |
2011 |
| Neutralization of Bothrops mattogrossensis snake venom from Bolivia: Experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation |
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No disponible |
2010 |
| Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain |
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No disponible |
2010 |
| The C-terminal region of a Lys49 myotoxin mediates Ca2þ influx in C2C12 myotubes |
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No disponible |
2010 |
| Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: Biochemical and toxicological characterization |
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No disponible |
2010 |
| Synthetic peptides derived from the C-terminal region of Lys49 phospholipase A2 homologues from Viperidae snake venoms: biomimetic activities and potential applications |
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No disponible |
2010 |
| Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective? |
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No disponible |
2010 |
| Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches |
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No disponible |
2010 |
| Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities |
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No disponible |
2010 |
| Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa |
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No disponible |
2010 |
| Intravenous administration of equine-derived whole IgG antivenom does not induce early adverse reactions in non-envenomed horses and cows |
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No disponible |
2010 |
| Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom |
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No disponible |
2010 |
| Dr. Clodomiro Picado Twight (1887-1944) |
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No disponible |
2010 |
| Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa |
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No disponible |
2010 |
| Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms |
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No disponible |
2010 |
| Snake venomics of Bothriechis nigroviridis reveals extreme variability among palm pitviper venoms: different evolutionary solutions for the same trophic purpose |
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No disponible |
2010 |
| Immunochemical and biological characterization of monoclonal antibodies against BaP1, a metalloproteinase from Bothrops asper snake venom |
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No disponible |
2010 |
| Snakebite envenoming from a global perspective: Towards an integrated approach |
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No disponible |
2010 |
| Backbone Flexibility Controls the Activity and Specificity of a Protein−Protein Interface: Specificity in Snake Venom Metalloproteases |
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No disponible |
2010 |
| The Global Snake Bite Initiative: an antidote for snake bite |
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No disponible |
2010 |
| Acute physiopathological effects of honeybee (Apis mellifera) envenoming by subcutaneous route in a mouse model |
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No disponible |
2010 |
| Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America |
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No disponible |
2010 |
| Wound exudate as a proteomic window to reveal different mechanisms of tissue damage by snake venom toxins |
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No disponible |
2009 |
| Calcium imaging of muscle cells treated with snake myotoxins reveals toxin synergism and presence of acceptors |
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No disponible |
2009 |
| Effects of Bothrops asper snake venom on the expression of cyclooxygenases and production of prostaglandins by peritoneal leukocytes in vivo, and by isolated neutrophils and macrophages in vitro |
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No disponible |
2009 |