USUARIOS REGISTRADOS
Ingrese con su correo institucional
Ingrese con su correo institucional
Unidad de Investigación
ID: 741
INSTITUTO CLODOMIRO PICADO
Mostrando 18 personas investigadoras
| NOMBRE |
|
CORREO ELECTRÓNICO |
|---|---|---|
| Acuña Espinola, Gabriel Angel | Inactivo | |
| Aguilar Ulloa, Wendy Maria | Inactivo | wendy.aguilarulloa@ucr.ac.cr |
| Alape Giron, Alberto | Activo | alberto.alape@ucr.ac.cr |
| Alfaro Chinchilla, Adriana | Activo | adriana.alfaro15@ucr.ac.cr |
| Altamirano Monge, Jose | Inactivo | |
| Araya Pizarro, Xavier Alberto | Activo | |
| Arce Estrada, Denice | Inactivo | |
| Arguedas Gómez, Mauricio José | Activo | mauricio.arguedasgomez@ucr.ac.cr |
| Arias Gomez, Berny | Inactivo | |
| Arias Rodríguez, Jazmín Melania | Inactivo | jazmin.arias@ucr.ac.cr |
| Bonilla Murillo, Fabián | Activo | fabian.bonilla@ucr.ac.cr |
| Boroschek Kraoskopf, Ruben | Inactivo | |
| Calvete Chornet, Juan José | Inactivo | jcalvete@ibv.csic.es |
| Calvo Corea, Silvia | Inactivo | |
| Camacho Umaña, Ericka | Activo | erika.camachoumana@ucr.ac.cr |
| Camacho Umaña, Erika Maria | Inactivo | |
| Castro Castro, Ana Cristina | Inactivo | |
| Castro Castro, Ana Cristina | Inactivo | ana.castrocastro@ucr.ac.cr |
Mostrando 90 personal colaborador
Mostrando 20 proyectos
Mostrando 20 proyectos en colaboración
Mostrando 638 publicaciones
| TÍTULO | TIPO | AUTOR | PROYECTOS | FECHA |
|---|---|---|---|---|
| Partial efficacy of a Brazilian coralsnake antivenom and Varespladib to neutralize distinct toxic effects induced by a sublethal Micrurus dumerilii carinicauda envenoming in rats |
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No disponible |
2022 |
| In vivo neutralization of Myotoxin II, a phospholipase A2 homolog from Bothrops asper venom, using peptides discovered via phage display technology |
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No disponible |
2022 |
| First insights into the venom composition of two Ecuadorian coral snakes |
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No disponible |
2022 |
| Solving the microheterogeneity of Bothrops asper myotoxin-II by high-resolution mass spectrometry: insights into C-terminal region variability in Lys49-phospholipase A2 homologs |
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No disponible |
2022 |
| Molecular architecture of the antiophidic protein DM64 and its binding specificity to myotoxin II from Bothrops asper venom |
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No disponible |
2022 |
| Proteomic and toxicological characterization of the venoms of the most enigmatic group of rattlesnakes: The long-tailed rattlesnakes |
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No disponible |
2022 |
| Proteomic and toxicological analysis of the venom of Micrurus yatesi and its neutralization by an antivenom |
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2022 | |
| The recovery from the neuroparalysis caused by Micrurus nigrocinctus venom is accelerated by an agonist of the CXCR4 receptor |
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No disponible |
2022 |
| In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom. |
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No disponible |
2022 |
| In vivo treatment with varespladib, a phospholipase A2 inhibitor, prevents the peripheral neurotoxicity and systemic disorders induced by Micrurus corallinus (coralsnake) venom in rats |
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No disponible |
2022 |
| In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors |
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2022 | |
| Promoting co-existence between humans and venomous snakes through increasing the herpetological knowledge base |
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No disponible |
2021 |
| Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms |
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No disponible |
2021 |
| Importance of mevalonate pathway lipids on the growth and survival of primary and metastatic gastric carcinoma cells |
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2021 | |
| The synthetic Varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins |
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No disponible |
2021 |
| Effect on cell growth, viability and migration of geraniol and geraniol-containing essential oil from Lippia alba (Verbenaceae) on gastric carcinoma cells |
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2021 | |
| Cytotoxicity of snake venom Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus |
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2021 | |
| Assessing a 6-h endpoint observation time in the lethality neutralization assay used to evaluate the preclinical efficacy of snake antivenoms |
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2021 | |
| Heterologous hyperimmune polyclonal antibodies against SARS-COV-2: A broad coverage, affordable, and scalable potential immunotherapy for Covid-19 |
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2021 | |
| The earless monitor lizard Lanthanotus borneensis – a venomous animal? |
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No disponible |
2021 |
| Venomics of the poorly studied hognosed pitvipers Porthidium arcosae and Porthidium volcanicum |
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2021 |
| Anexo 5: Guías de la OMS para la producción, control y regulación de inmunoglobulinas antiveneno de serpiente |
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No disponible |
2021 |
| High Efficacy of Therapeutic Equine Hyperimmune Antibodies Against SARS-CoV-2 Variants of Concern |
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2021 | |
| What’s in a mass |
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No disponible |
2021 |
| Cardiac effect induced by Crotalus durissus cascavella venom: morphofunctional evidence and mechanism of action |
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No disponible |
2021 |
| Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance |
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No disponible |
2021 |
| Localization of Myotoxin I and Myotoxin II from the venom of Bothrops asper in a murine model |
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2021 | |
| Varespladib (LY315920) and methyl Varespladib (LY333013) abrogate or delay lethality induced by presynaptically-acting neurotoxic snake venoms |
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No disponible |
2020 |
| Manual de Métodos Inmunológicos |
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No disponible |
2020 |
| An interactive database for the investigation of high-density peptide microarray guided interaction patterns and antivenom cross-reactivity |
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No disponible |
2020 |
| Development of nanobodies against hemorrhagic and myotoxic components of Bothrops atrox snake venom |
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No disponible |
2020 |
| Venom diversity in the neotropical genus Tityus: implications for antivenom design emerging from molecular and immunochemical analyses across endemic areas of scorpionism |
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No disponible |
2020 |
| Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: identification of the first lethal multimeric neurotoxin in coral snake venom |
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No disponible |
2020 |
| Novel snakebite therapeutics must be tested in appropriate rescue models to robustly assess their preclinical efficacy |
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No disponible |
2020 |
| Comparative biochemical characterization of Viperidae snake venoms from Perú reveals two compositional patterns of phospholipase A2 expression |
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No disponible |
2020 |
| Venomics of the Duvernoy's gland secretion of the false coral snake Rhinobothryum bovallii (Andersson, 1916) and assessment of venom lethality towards synapsid and diapsid animal models |
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No disponible |
2020 |
| 12-HETE is a regulator of PGE2 production via COX-2 expression induced by a snake venom group IIA phospholipase A2 in isolated peritoneal macrophages |
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No disponible |
2020 |
| Ontogenetic variation in the venom of Mexican Jumping Viper (Metlapilcoatlus nummifer) |
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No disponible |
2020 |
| Preadipocytes are target cells for the actions of a representative gIIA phospholipase A2 which triggers proinflammatory pathways related to obesity |
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No disponible |
2020 |
| Snake venomics, experimental toxic activities and clinical characteristics of human envenomation by Bothrocophias myersi (Serpentes: Viperidae) from Colombia |
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No disponible |
2020 |
| Oral administration of Costa Rican guava (Psidium friedrichsthalianum) juice induces changes in urinary excretion of energy-related compounds in Wistar rats determined by 1H NMR |
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2020 | |
| Tratamientos COVID-19 |
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No disponible |
2020 |
| Unity makes strength: exploring intra and interspecies toxin synergism between phospholipases A2 and cytotoxins |
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No disponible |
2020 |
| Danger in the canopy: comparative proteomics and bioactivities of the venoms of the South American palm viper Bothrops bilineatus subspecies bilineatus and smaragdinus, and antivenomics of B. b. bilineatus (Rondônia) venom against the Brazilian pentabothropic antivenom |
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No disponible |
2020 |
| Immunological cross-recognition and neutralization studies of Micrurus mipartitus and Micrurus dumerilii venoms by two therapeutic equine antivenoms |
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2020 | |
| Proteogenomic analysis of the Clostridium difficile exoproteome reveals a correlation between phylogenetic distribution and virulence potential |
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2020 | |
| A lipidomic perspective of the action of group IIA secreted phospholipase A2 on human monocytes: lipid droplet biogenesis and activation of cytosolic phospholipase A2α |
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No disponible |
2020 |
| Mevalonate pathway as a novel target for the treatment of metastatic gastric cancer |
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2020 |
| Editorial: Novel immunotherapies against envenomings by snakes and other venomous animals |
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No disponible |
2020 |
| Venom variation in Bothrops asper lineages from north-western South America. |
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No disponible |
2020 |
| Genetic and toxinological divergence among populations of Tityus trivittatus Kraepelin, 1898 (Scorpiones: Buthidae) inhabiting Paraguay and Argentina |
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No disponible |
2020 |
| Potent virucidal activity against Flaviviridae of a group IIA phospholipase A2 isolated from the venom of Bothrops asper |
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2020 | |
| Métodos de Investigación: destrezas básicas para el trabajo científico en las disciplinas biomédicas |
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No disponible |
2020 |
| Venomics of the Central American Lyre snake Trimorphodon quadruplex (Colubridae: Smith, 1941) from Costa Rica |
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No disponible |
2020 |
| Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: comparative characterization and synergism between Asp49 and Lys49 variants |
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2019 | |
| Differences in plasmatic butyrylcholinesterases (BChE) values between Pacific and Caribbean populations of terciopelo (Bothrops asper) in Costa Rica |
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2019 | |
| A secreted phospholipase A2 induces formation of smooth muscle foam cells which trans-differentiate to macrophage-like state |
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No disponible |
2019 |
| New insights into the phylogeographic distribution of the 3FTx/PLA2 venom dichotomy across genus Micrurus in South America |
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2019 | |
| Cloning, purification and characterization of nigrelysin, a novel actinoporin from the sea anemone Anthopleura nigrescens |
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No disponible |
2019 |
| Three-finger toxins from the venom of Micrurus tschudii (desert coral snake): isolation and characterization of tschuditoxin-I |
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2019 | |
| Proteomic profiling, functional characterization, and immunoneutralization of the venom of Porthidium porrasi, a pitviper endemic to Costa Rica |
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2019 | |
| Venom characterization of the bark scorpion Centruroides edwardsii (Gervais 1843): composition, biochemical activities and in vivo toxicity for potential prey |
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2019 | |
| Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species |
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2019 | |
| Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920) |
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2019 | |
| Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro |
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2019 | |
| Enzymatic labelling of venom phospholipase A2 toxins |
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No disponible |
2019 |
| Physical characteristics of nano-Hydroxyapatite Pickering-emulsions and their adjuvant activity on the antibody response towards the Bothros asper snake venom |
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No disponible |
2019 |
| Neutralizing properties of Varespladib toward group I and II myotoxic phospholipases A2 |
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2019 | |
| Caracterización proteómica, funcional e inmunoneutralización del veneno de la serpiente Porthidium porrasi de Costa Rica |
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No disponible |
2019 |
| Reflexiones desde la academia. Universidad, ciencia y sociedad |
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No disponible |
2019 |
| First look into the venom of Roatan Island´s critically endangered coral snake Micrurus ruatanus: proteomic characterization, toxicity, immunorecognition and neutralization by an antivenom |
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2019 | |
| Novel three-finger toxins from Micrurus dumerilii and Micrurus mipartitus coral snake venoms: phylogenetic relationships and characterization of Clarkitoxin-I-Mdum |
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2019 | |
| Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric β-neurotoxin |
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No disponible |
2019 |
| A myotoxic Lys49 phospholipase A2-homologue is the major component of the venom of Bothrops cotiara from Misiones, Argentina |
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2018 | |
| Depletion of complement enhances the clearance of Brucella abortus in mice |
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2018 | |
| Intravascular hemolysis induced by phospholipases A2 from the venom of the Eastern coral snake, Micrurus fulvius: functional profile of hemolytic and non-hemolytic isoforms |
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2018 | |
| MipLAAO, a new L-amino acid oxidase from the redtail coral snake, Micrurus mipartitus |
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2018 | |
| Nociones de Inmunologia |
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No disponible |
2018 |
| Cannibalism by large tadpoles of Rhinophrynus dorsalis (Anura: Rhinophrynidae) |
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No disponible |
2018 |
| A snake venom secreted phospholipase A2 induces foam cell formation depending on the activation of factors involved in lipid homeostasis |
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No disponible |
2018 |
| Innovative immunization strategies for antivenom development |
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No disponible |
2018 |
| Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms |
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No disponible |
2018 |
| Delayed oral LY333013 rescues mice from highly neurotoxic, lethal doses of Papuan Taipan (Oxyuranus scutellatus) venom |
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No disponible |
2018 |
| Pros and cons of different therapeutic antibody formats for recombinant antivenom development |
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No disponible |
2018 |
| Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity |
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2018 | |
| Prolonged development of the middle ear in Rhinella horribilis |
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No disponible |
2018 |
| Effect of exposition to chlorpyrifos upon plasmatic cholinesterases, hematology and blood biochemistry values in Bothrops asper (Serpentes: Viperidae) |
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2018 | |
| Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus |
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2018 | |
| Biological and proteolytic variation in the venom of Crotalus scutulatus scutulatus from Mexico |
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No disponible |
2018 |
| Myotoxin-neutralizing peptides |
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No disponible |
2018 |
| A novel pentameric phospholipase A2 myotoxin (PophPLA2) from the venom of the pit viper Porthidium ophryomegas |
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2018 | |
| In vivo neutralization of the dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG monoclonal antibodies |
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No disponible |
2018 |
| Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead |
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No disponible |
2017 |
| Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms |
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No disponible |
2017 |
| Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect |
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No disponible |
2017 |
| Detection of a synthetic sex steroid in the American crocodile (Crocodylus acutus): Evidence for a novel environmental androgen |
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2017 | |
| Exploring the venom of the forest cobra snake: Toxicovenomics and antivenom profiling of Naja melanoleuca |
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No disponible |
2017 |
| Comparison of the adjuvant activity of emulsions with different physicochemical properties on the antibody response towards the venom of West African carpet viper (Echis ocellatus) |
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2017 | |
| High-density peptide microarray exploration of the antibody response in a rabbit immunized with a neurotoxic venom fraction |
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No disponible |
2017 |
| Physicochemical characterization of Jicaro seeds (Crescentia alata H.B.K.): a novel protein-rich and oleaginous seed |
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No disponible |
2017 |
| Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping |
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No disponible |
2017 |
| Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster” |
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No disponible |
2017 |
| Pitfalls to avoid when using phage display for snake toxins |
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No disponible |
2017 |
| Exploration of immunoglobulin transcriptomes from mice immunized with three-finger toxins and phospholipases A2 from the Central American coral snake, Micrurus nigrocinctus |
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No disponible |
2017 |
| Screening for target toxins of the antiophidic protein DM64 through a gel-based interactomics approach |
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No disponible |
2017 |
| Primary structures and partial toxicological characterization of two phospholipases A2 from Micrurus mipartitus and Micrurus dumerilii coral snake venoms |
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2017 | |
| Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom |
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No disponible |
2017 |
| Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis) |
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No disponible |
2017 |
| Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles) |
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2017 | |
| Proteoform-resolved quantitative venomics: looking through a crystal ball |
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No disponible |
2017 |
| Understanding and confronting snakebite envenoming: The harvest of cooperation |
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No disponible |
2016 |
| Novel catalytically-inactive PII metalloproteinases from a viperid snake venom with substitutions in the canonical zinc-binding motif |
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2016 | |
| Novel insights into capillary vessel basement membrane damage by snake venom hemorrhagic metalloproteinases: A biochemical and immunohistochemical study |
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No disponible |
2016 |
| Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: proteome, toxicity, and cross-neutralization by antivenom |
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2016 | |
| From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy |
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No disponible |
2016 |
| High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays |
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No disponible |
2016 |
| Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii |
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No disponible |
2016 |
| Regional warming and the thermal regimes of American crocodile nests in the Tempisque Basin, Costa Rica |
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No disponible |
2016 |
| Toxicovenomics and antivenom profiling of the Eastern green mamba snake (Dendroaspis angusticeps). |
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No disponible |
2016 |
| Larval aggression is independent of food limitation in nurseries of a poison frog |
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No disponible |
2016 |
| Divergent functional profiles of acidic and basic phospholipases A2 in the venom of the snake Porthidium lansbergii lansbergii |
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2016 | |
| Brucella abortus Strain 2308 Wisconsin Genome: Importance of the Definition of Reference Strains |
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No disponible |
2016 |
| Methyltestosterone alters sex determination in the American alligator (Alligator mississippiensis) |
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No disponible |
2016 |
| Hemorrhage Caused by Snake Venom Metalloproteinases: A Journey of Discovery and Understanding |
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No disponible |
2016 |
| Venomic analysis of the poorly studied desert coral snake, Micrurus tschudii tschudii, supports the 3FTx/PLA2 dichotomy across Micrurus venoms |
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No disponible |
2016 |
| Desarrollo de la herpetocultura en Costa Rica: Situación actual de herpetarios y manejo ex situ de reptiles y anfibios |
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No disponible |
2016 |
| Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab0)2 and whole IgG antivenoms |
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No disponible |
2016 |
| Muscle Tissue Damage Induced by the Venom of Bothrops asper: Identification of Early and Late Pathological Events through Proteomic Analysis |
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No disponible |
2016 |
| N-terminal peptide of myotoxin II from Bothrops asper venom enhances the activity of endothelin converting enzyme and neprilysin |
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No disponible |
2016 |
| The need for an integrated approach in confronting snakebite envenoming in Latin America: the relevance of endogenous scientific and technological research |
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No disponible |
2016 |
| Hydrology Affects Environmental and Spatial Structuring of Microalgal Metacommunities in Tropical Pacific Coast Wetlands |
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2016 | |
| Mecanismo de açao dos venenos de cobras corais |
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No disponible |
2016 |
| Preclinical evaluation of three polyspecific antivenoms against the venom of Echis ocellatus: Neutralization of toxic activities and antivenomics |
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No disponible |
2016 |
| Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2 |
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No disponible |
2016 |
| Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the Brazilian Atlantic rainforest |
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No disponible |
2016 |
| Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice |
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No disponible |
2016 |
| A cryptic palm-pitviper species (Squamata: Viperidae: Bothriechis) from the Costa Rican highlands, with notes on the variation within B. nigroviridis |
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No disponible |
2016 |
| Bacterial Sphingomyelinases and Phospholipases as Virulence Factors |
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2016 | |
| Venoms of Micrurus coral snakes: evolutionary trends in compositional patterns emerging from proteomic analyses |
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2016 | |
| Actividad letal de seis venenos de serpientes de importancia médica en el Ecuador |
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No disponible |
2016 |
| Metaloproteinasas dependientes de Zinc: Protagonistas centrales en la Fisiopatología de Envenenamientos por Serpientes de la familia Viperidae |
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No disponible |
2016 |
| Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom |
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No disponible |
2016 |
| Venom of the Coral Snake Micrurus clarki: Proteomic Profile, Toxicity, Immunological Cross-Neutralization, and Characterization of a Three-Finger Toxin |
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No disponible |
2016 |
| First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis |
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2015 | |
| Effect of geographical variation of Echis ocellatus, Naja nigricollis and Bitis arietans venoms on their neutralization by homologous and heterologous antivenoms |
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No disponible |
2015 |
| Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: identification of key toxin targets for antivenom development. |
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No disponible |
2015 |
| Lachesis stenophrys venom reduces the equine antibody response towards Bothrops asper venom used as co-immunogen in the production of polyspecific snake antivenom |
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2015 | |
| A bright future for integrative venomics |
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No disponible |
2015 |
| MmTX1 and MmTX2 from coral snake venom potently modulate GABAA receptor activity |
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No disponible |
2015 |
| Group-II phospholipase A2 enzymes |
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No disponible |
2015 |
| Membrane-damaging and cytotoxic sphingomyelinases and phospholipases |
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No disponible |
2015 |
| Multiple paths to aquatic specialisation in four species of Central American Anolis lizards |
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No disponible |
2015 |
| Seasonal wetlands in the Pacific coast of Costa Rica and Nicaragua: environmental characterisation and conservation status |
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2015 | |
| Purification of equine whole IgG snake antivenom by using an aqueous two phase system as a primary purification step |
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2015 | |
| Extracts of Renealmia alpinia (Rottb.) MAAS Protect against Lethality and Systemic Hemorrhage Induced by Bothrops asper Venom: Insights from a Model with Extract Administration before Venom Injection |
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No disponible |
2015 |
| A constant area monolayer method to assess optimal lipid packing for lipolysis tested with several secreted phospholipases A2 |
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2015 | |
| Assessing endotoxins in equine-derived snake antivenoms: Comparison of the USP pyrogen test and the Limulus Amoebocyte Lysate assay (LAL) |
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2015 | |
| Snake venomics of monocled cobra (Naja kaouthia) and investigation of human IgG response against venom toxins |
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No disponible |
2015 |
| Phospholipases a2 from Viperidae snakes: Differences in membranotropic activity between enzymatically active toxin and its inactive isoforms |
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No disponible |
2015 |
| A Call for Incorporating Social Research in the Global Struggle against Snakebite |
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No disponible |
2015 |
| Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids |
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No disponible |
2015 |
| Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score |
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No disponible |
2015 |
| Snakebites are associated with poverty, weather fluctuations, and El Niño |
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No disponible |
2015 |
| The lethality test used for estimating the potency of antivenoms against Bothrops asper snake venom: Pathophysiological mechanisms, prophylactic analgesia, and a surrogate in vitro assay |
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2015 | |
| Brucella abortus Induces the Premature Death of Human Neutrophils through the Action of Its Lipopolysaccharide |
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No disponible |
2015 |
| Minipool Caprylic Acid Fractionation of Plasma Using Disposable Equipment: A Practical Method to Enhance Immunoglobulin Supply in Developing Countries |
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No disponible |
2015 |
| Índices bibliométricos y revistas de ‘corriente central’: implicaciones para el desarrollo de las ciencias naturales en Costa Rica |
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No disponible |
2015 |
| Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis |
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No disponible |
2015 |
| Antivenomics: a proteomics tool for studying the immunoreactivity of antivenoms |
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2015 | |
| Brucella canis Is an Intracellular Pathogen That Induces a Lower Proinflammatory Response than Smooth Zoonotic Counterparts |
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2015 | |
| Improved biomass and protein production in solid-state cultures of an Aspergillus sojae strain harboring the Vitreoscilla hemoglobin |
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No disponible |
2015 |
| Evaluation of the preclinical efficacy of four antivenoms, distributed in sub-Saharan Africa, to neutralize the venom of the carpet viper, Echis ocellatus, from Mali, Cameroon, and Nigeria |
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No disponible |
2015 |
| Venomics and antivenomics of Bothrops erythromelas from five geographic populations within the Caatinga ecoregion of northeastern Brazil |
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No disponible |
2015 |
| Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage |
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No disponible |
2015 |
| Phospholipase A2 enhances the endothelial cell detachment effect of a snake venom metalloproteinase in the absence of catalysis |
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2015 | |
| Proteomic and functional analysis of the venom of Porthidium lansbergii lansbergii (Lansberg’s hognose viper) from the Atlantic Department of Colombia |
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No disponible |
2015 |
| Utilidad de los péptidos sintéticos en estudios de estructura-función e identificación de epitopos en toxinas |
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No disponible |
2014 |
| Venomous snakes of Costa Rica: biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics |
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2014 | |
| Proteomic and functional profiling of the venom of Bothrops ayerbei from Cauca, Colombia, reveals striking interspecific variation with Bothrops asper venom |
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2014 | |
| Immunological profile of antivenoms: preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays |
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No disponible |
2014 |
| Critical role of TLR2 and MyD88 for functional response of macrophages to a group IIA-Secreted phospholipase A2 from snake venom |
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No disponible |
2014 |
| Anticomplementary Activity of Horse IgG and F(ab’)2 Antivenoms |
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No disponible |
2014 |
| Antivenomic Characterization of Two Antivenoms Against the Venom of the Taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia |
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No disponible |
2014 |
| Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms |
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No disponible |
2014 |
| Snakebite Envenomingin Latin America and the Caribbean |
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No disponible |
2014 |
| Effect of the metalloproteinase inhibitor batimastat in the systemic toxicity induced by Bothrops asper snake venom: understanding the role of metalloproteinases in envenomation |
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2014 | |
| Tissue Damage and Inflammation Induced by Snake Venoms |
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No disponible |
2014 |
| Proteomic and toxicological profiling of the venom of Bothrocophias campbelli, a pitviper species from Ecuador and Colombia |
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2014 | |
| Intravascular hemolysis induced by the venom of the Eastern coral snake, Micrurus fulvius, in a mouse model: Identification of directly hemolytic phospholipases A2 |
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No disponible |
2014 |
| Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: An antivenomics and neutralization study |
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2014 | |
| The analgesics morphine and tramadol do not alter the acute toxicity induced by Bothrops asper snake venom in mice |
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No disponible |
2014 |
| An Asp49 Phospholipase A2 from Snake Venom Induces Cyclooxygenase-2 Expression and Prostaglandin E2 Production via Activation of NF-κB, p38MAPK, and PKC in Macrophages |
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No disponible |
2014 |
| Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus |
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No disponible |
2014 |
| Comparison of the adjuvant activity of aluminum hydroxide and calcium phosphate on the antibody response towards Bothrops asper snake venom |
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No disponible |
2014 |
| A neutralizing recombinant single chain antibody, scFv, against BaP1, A P-I hemorrhagic metalloproteinase from Bothrops asper snake venom |
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No disponible |
2014 |
| Current challenges for confronting the public health problem of snakebite envenoming in Central America |
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No disponible |
2014 |
| Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica |
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No disponible |
2014 |
| Industrial Production and Quality Control of Snake Antivenoms |
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No disponible |
2014 |
| Reducing the impact of snakebite envenoming in Latin America and the Caribbean: achievements and challenges ahead |
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No disponible |
2014 |
| Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo |
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2014 | |
| Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: Comparison of their stability in an accelerated test |
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No disponible |
2014 |
| Snake venomics of Bothrops punctatus, a semi-arboreal pitviper species from Antioquia, Colombia |
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No disponible |
2014 |
| Venomics of new world pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon |
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2014 | |
| A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms |
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No disponible |
2014 |
| Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka |
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2014 | |
| A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming |
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No disponible |
2014 |
| Epidemiology of rapes in Costa Rica: Characterization of victims, perpetrators and circumstances surrounding forced intercourse |
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No disponible |
2014 |
| Two color morphs of the pelagic yellow-bellied sea snake, pelamis platura, from different locations of Costa Rica: snake venomics, toxicity, and neutralization by antivenom |
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2014 | |
| Role of enzymatic activity inmuscle damage and cytotoxicity induced by Bothrops asper Asp49 phospholipase A2 myotoxins: are there additional effector mechanisms involved? |
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No disponible |
2014 |
| Evidence of maternal provisioning of alkaloid-based chemical defenses in the strawberry poison frog Oophaga pumilio |
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No disponible |
2014 |
| Understanding structural and functional aspects of PII snake venom metalloproteinases: Characterization of BlatH1, a hemorrhagic dimeric enzyme from the venom of Bothriechis lateralis |
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No disponible |
2014 |
| Suero antiofidico polivalente |
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No disponible |
2013 |
| The Need for Full Integration of Snakebite Envenoming within a Global Strategy to Combat the Neglected Tropical Diseases: The Way Forward |
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No disponible |
2013 |
| Suero antiofídico anti-coral |
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No disponible |
2013 |
| Proteomic analysis of Bothrops pirajai snake venom and characterization of BpirMP, a new P-I metalloproteinase |
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No disponible |
2013 |
| Comparison of venom composition and biological activities of the subspecies Crotalus lepidus lepidus, Crotalus lepidus klauberi and Crotalus lepidus morulus from Mexico |
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No disponible |
2013 |
| Generalidades de serpientes venenosas en Costa Rica |
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No disponible |
2013 |
| Guía de información: Serpientes de Costa Rica y prevención de mordeduras |
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No disponible |
2013 |
| Tratamiento hospitalario del envenenamiento por mordedura de serpiente |
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No disponible |
2013 |
| Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus |
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No disponible |
2013 |
| A catalytically-inactive snake venom Lys49 phospholipase A2 homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages |
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No disponible |
2013 |
| Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics |
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No disponible |
2013 |
| Polyspecific Antivenom Liquid |
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No disponible |
2013 |
| A Lys49 Phospholipase A2, Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region |
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No disponible |
2013 |
| Role of the animal model on the pharmacokinetics of equine-derived antivenoms |
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No disponible |
2013 |
| Instituto Clodomiro Picado |
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No disponible |
2013 |
| Algoritmo para el diagnóstico y tratamiento con antivenenos en pacientes mordidos por serpientes en Centroamérica |
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No disponible |
2013 |
| Amino acid sequence and biological characterization of BlatPLA2, a non-toxic acidic phospholipase A2 from the venom of the arboreal snake Bothriechis lateralis from Costa Rica |
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2013 | |
| Antivenom for snakebite envenoming in Sri Lanka: The need for geographically specific antivenom and improved efficacy |
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No disponible |
2013 |
| Using Geographical Information Systems to Identify Populations in Need of Improved Accessibility to Antivenom Treatment for Snakebite Envenoming in Costa Rica |
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No disponible |
2013 |
| New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India |
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No disponible |
2013 |
| Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies |
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No disponible |
2013 |
| Preclinical assessment of a polyspecific antivenom against the venoms of Cerrophidion sasai, Porthidium nasutum and Porthidium ophryomegas: Insights from combined antivenomics and neutralization assays |
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No disponible |
2013 |
| Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins – distinct mechanisms of action |
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No disponible |
2013 |
| Phospholipases A2: Unveiling the secrets of a functionally versatile group of snake venom toxins |
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No disponible |
2013 |
| Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture |
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No disponible |
2013 |
| Systemic effects induced by the venom of the snake Bothrops caribbaeus in a murine model |
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No disponible |
2013 |
| Snake venomics of Lachesis muta rhombeata and genus-wide antivenomics assessment of the paraspecific immunoreactivity of two antivenoms evidence the high compositional and immunological conservation across Lachesis |
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No disponible |
2013 |
| Biochemical and biological characterization of two serine proteinases from Colombian Crotalus durissus cumanensis snake venom |
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No disponible |
2013 |
| Why myotoxin-containing snake venoms possess powerful nucleotidases? |
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No disponible |
2013 |
| Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms |
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No disponible |
2013 |
| Venenos de serpiente: de la investigación al tratamiento |
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No disponible |
2012 |
| Snake venomics and toxicological profiling of the arboreal pitviper Bothriechis supraciliaris from Costa Rica |
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No disponible |
2012 |
| Investigación científica y tecnológica en el Instituto Clodomiro Picado: Una perspectiva bibliométrica de cuatro décadas (1970-2010) |
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No disponible |
2012 |
| Implementación de un laboratorio de análisis proteómicos en el Instituto Clodomiro Picado (UCR): primeras experiencias en Costa Rica |
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No disponible |
2012 |
| Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab0)2] antivenoms, in Bothrops asper bites in Colombia |
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