Juan José Calvete Chornet

Investigador(a)

Correo electrónico: jcalvete@ibv.csic.es

Categoría Regimen Académico: PROF. INTERINO LIC.
Grado Académico: Ph.D.
Unidad Base: INSTITUTO CLODOMIRO PICADO

Proyectos
Publicaciones Kérwá

Proyectos

Mostrando 1 proyectos

Núm. de proyecto	Descripción	Unidad de Investigación	Todos DESARROLLO TERMINADO VENCIDO
B7608	TENDENCIAS EVOLUTIVAS EN LOS PATRONES DE COMPOSICIÓN DE TOXINAS EN VENENOS DE SERPIENTES CORAL DEL CONTINENTE AMERICANO (MICRURUS: ELAPIDAE)	Instituto Clodomiro Picado	Terminado

Distinciones

Distinción	Año	Entidad	Ámbito	Descripción
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BECAS

País	Entidad	Año de inicio	Año de término	Descripción
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Publicaciones

Mostrando 81 publicaciones

TÍTULO	TIPO	FECHA	PROYECTO
Mandibular gland proteomics of the Mexican alligator lizard, Abronia graminea, and the red-lipped arboreal alligator lizard, Abronia lythrochila	artículo original	2024	No disponible
Assessing target specificity of the small molecule inhibitor MARIMASTAT to snake venom toxins: a novel application of thermal proteome profiling	artículo original	2024	No disponible
Proteomic analysis of the mandibular glands from the Chinese crocodile lizard, Shinisaurus crocodilurus – another venomous lizard?	artículo original	2023	No disponible
Quantification of snake venom proteomes by mass spectrometry-considerations and perspectives.	artículo original	2023	No disponible
Half a century of research on Bothrops asper venom variation: biological and biomedical implications	artículo original	2022	No disponible
Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance	artículo original	2021	No disponible
The earless monitor lizard Lanthanotus borneensis – a venomous animal?	artículo original	2021	No disponible
Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms	artículo original	2021	No disponible
What’s in a mass	artículo de revisión	2021	No disponible
Venomics of the poorly studied hognosed pitvipers Porthidium arcosae and Porthidium volcanicum	artículo original	2021	C0071
Venom variation in Bothrops asper lineages from north-western South America.	artículo original	2020	No disponible
Danger in the canopy: comparative proteomics and bioactivities of the venoms of the South American palm viper Bothrops bilineatus subspecies bilineatus and smaragdinus, and antivenomics of B. b. bilineatus (Rondônia) venom against the Brazilian pentabothropic antivenom	artículo original	2020	No disponible
Venomics of the Duvernoy's gland secretion of the false coral snake Rhinobothryum bovallii (Andersson, 1916) and assessment of venom lethality towards synapsid and diapsid animal models	artículo original	2020	No disponible
Comparative biochemical characterization of Viperidae snake venoms from Perú reveals two compositional patterns of phospholipase A2 expression	artículo original	2020	No disponible
New insights into the phylogeographic distribution of the 3FTx/PLA2 venom dichotomy across genus Micrurus in South America	artículo original	2019	B7608
A novel pentameric phospholipase A2 myotoxin (PophPLA2) from the venom of the pit viper Porthidium ophryomegas	artículo original	2018	B5602
Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead	artículo original	2017	No disponible
Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis)	artículo original	2017	No disponible
Proteoform-resolved quantitative venomics: looking through a crystal ball	artículo original	2017	No disponible
Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms	artículo original	2017	No disponible
Venomic analysis of the poorly studied desert coral snake, Micrurus tschudii tschudii, supports the 3FTx/PLA2 dichotomy across Micrurus venoms	artículo original	2016	No disponible
Combined venomics, venom gland transcriptomics, bioactivities, and antivenomics of two Bothrops jararaca populations from geographic isolated regions within the Brazilian Atlantic rainforest	artículo original	2016	No disponible
Venoms of Micrurus coral snakes: evolutionary trends in compositional patterns emerging from proteomic analyses	artículo original	2016	B3760
Preclinical evaluation of three polyspecific antivenoms against the venom of Echis ocellatus: Neutralization of toxic activities and antivenomics	artículo original	2016	No disponible
Novel catalytically-inactive PII metalloproteinases from a viperid snake venom with substitutions in the canonical zinc-binding motif	artículo original	2016	B2517 B0528
Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii	artículo original	2016	No disponible
First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis	artículo original	2015	B4100
Venomics and antivenomics of Bothrops erythromelas from five geographic populations within the Caatinga ecoregion of northeastern Brazil	artículo original	2015	No disponible
A Call for Incorporating Social Research in the Global Struggle against Snakebite	artículo original	2015	No disponible
Evaluation of the preclinical efficacy of four antivenoms, distributed in sub-Saharan Africa, to neutralize the venom of the carpet viper, Echis ocellatus, from Mali, Cameroon, and Nigeria	artículo original	2015	No disponible
A bright future for integrative venomics	artículo original	2015	No disponible
Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids	artículo original	2015	No disponible
Antivenomics: a proteomics tool for studying the immunoreactivity of antivenoms	capítulo de libro	2015	B2652
Tissue Localization and Extracellular Matrix Degradation by PI, PII and PIII Snake Venom Metalloproteinases: Clues on the Mechanisms of Venom-Induced Hemorrhage	artículo original	2015	No disponible
Understanding structural and functional aspects of PII snake venom metalloproteinases: Characterization of BlatH1, a hemorrhagic dimeric enzyme from the venom of Bothriechis lateralis	artículo original	2014	No disponible
Immunological profile of antivenoms: preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays	artículo original	2014	No disponible
Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms	artículo original	2014	No disponible
Venomics of new world pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon	artículo original	2014	B2652
A multicomponent strategy to improve the availability of antivenom for treating snakebite envenoming	artículo original	2014	No disponible
Two color morphs of the pelagic yellow-bellied sea snake, pelamis platura, from different locations of Costa Rica: snake venomics, toxicity, and neutralization by antivenom	artículo preliminar	2014	B2652 B3760
Combined venom gland cDNA sequencing and venomics of the New Guinea small-eyed snake, Micropechis ikaheka	artículo original	2014	B2652
Preclinical efficacy of Australian antivenoms against the venom of the small-eyed snake, Micropechis ikaheka, from Papua New Guinea: An antivenomics and neutralization study	artículo original	2014	B2652
Venomous snakes of Costa Rica: biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics	artículo original	2014	B3760 A7611
Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus	artículo original	2014	No disponible
Amino acid sequence and biological characterization of BlatPLA2, a non-toxic acidic phospholipase A2 from the venom of the arboreal snake Bothriechis lateralis from Costa Rica	artículo original	2013	A9513
Integrated “omics” profiling indicates that miRNAs are modulators of the ontogenetic venom composition shift in the Central American rattlesnake, Crotalus simus simus	artículo original	2013	No disponible
Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics	artículo original	2013	No disponible
Snake venomics of Lachesis muta rhombeata and genus-wide antivenomics assessment of the paraspecific immunoreactivity of two antivenoms evidence the high compositional and immunological conservation across Lachesis	artículo original	2013	No disponible
The Need for Full Integration of Snakebite Envenoming within a Global Strategy to Combat the Neglected Tropical Diseases: The Way Forward	artículo original	2013	No disponible
Preclinical assessment of a polyspecific antivenom against the venoms of Cerrophidion sasai, Porthidium nasutum and Porthidium ophryomegas: Insights from combined antivenomics and neutralization assays	artículo original	2013	No disponible
New approaches & technologies of venomics to meet the challenge of human envenoming by snakebites in India	artículo original	2013	No disponible
Snake venomics and toxicological profiling of the arboreal pitviper Bothriechis supraciliaris from Costa Rica	artículo original	2012	No disponible
Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in venom toxicity	artículo original	2012	No disponible
Identification of New Snake Venom Metalloproteinase Inhibitors Using Compound Screening and Rational Peptide Design	artículo original	2012	No disponible
Second generation snake antivenomics: Comparing immunoaffinity and immunodepletion protocols	artículo original	2012	No disponible
Snake venomics of the pit vipers Porthidium nasutum, Porthidium ophryomegas, and Cerrophidion godmani from Costa Rica: Toxicological and taxonomical insights	artículo original	2012	No disponible
Resurrexit, sicut dixit, alleluia. Snake venomics from a 26-years old polyacrylamide focusing gel	artículo original	2012	No disponible
Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: Keys to understand the variable immune response in horses	artículo original	2012	No disponible
Snake venomics of crotalus tigris: the minimalist toxin arsenal of the deadliest neartic rattlesnake venom: evolutionary clues for generating a pan-specific antivenom against crotalid type II venoms	artículo original	2012	No disponible
Ending the drought: New strategies for improving the flow of affordable, effective antivenoms in Asia and Africa	artículo original	2011	No disponible
Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing	artículo original	2011	No disponible
Snake Venomics of African Spitting Cobras: Toxin Composition and Assessment of Congeneric Cross-Reactivity of the Pan-African EchiTAb-Plus-ICP Antivenom by Antivenomics and Neutralization Approaches	artículo original	2011	A9003
Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management	artículo original	2011	No disponible
Comparative study of the cytolytic activity of snake venoms from African spitting cobras (Naja spp., Elapidae) and its neutralization by a polyspecific antivenom	artículo original	2011	A9513
Venomic and antivenomic analyses of the Central American coral snake, Micrurus nigrocinctus (Elapidae)	artículo original	2011	No disponible
Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa	artículo original	2010	No disponible
Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: Biochemical and toxicological characterization	artículo original	2010	No disponible
Impact of Regional Variation in Bothrops asper Snake Venom on the Design of Antivenoms: Integrating Antivenomics and Neutralization Approaches	artículo original	2010	No disponible
Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities	artículo original	2010	No disponible
Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa	artículo original	2010	No disponible
Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America	artículo original	2010	No disponible
Snake venomics of Bothriechis nigroviridis reveals extreme variability among palm pitviper venoms: different evolutionary solutions for the same trophic purpose	artículo original	2010	No disponible
Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Perú and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism	artículo original	2009	No disponible
Venom, venomics, antivenomics	artículo original	2009	A8521
Snake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing to its taxonomy and snakebite management	artículo original	2009	No disponible
Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming	artículo original	2009	No disponible
Isolation and characterization of a serine proteinase with thrombin-like activity from the venom of the snake Bothrops asper	artículo original	2008	No disponible
Snake Venomics of Central American Pitvipers: Clues for Rationalizing the Distinct Envenomation Profiles of Atropoides nummifer and Atropoides picadoi	artículo original	2008	No disponible
Snake venomics of the South and Central American Bushmasters. Comparison of the toxin composition of Lachesis muta gathered from proteomic versus transcriptomic analysis	artículo original	2008	No disponible
Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with Toxicological Activities and Immunoreactivity of a Heterologous Antivenom	artículo original	2008	No disponible
Snake Venomics and Antivenomics of the Arboreal Neotropical Pitvipers Bothriechis lateralis and Bothriechis schlegelii	artículo original	2008	No disponible