| Serum immunoglobulin levels in Cabécar and Guaymí Indians in Southeastern Costa Rica/Serum immunoglobulin levels in Cabécar and Guaymí Indians in Southeastern Costa Rica |
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No disponible
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| Publicaciones científicas de Costa Rica en el Science Citation Index: análisis bibliométricos del trienio 1999-2001/Publicaciones científicas de Costa Rica en el Science Citation Index: análisis bibliométricos del trienio 1999-2001 |
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No disponible
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| Isolation of bothrasperin, a disintegrin with potent platelet aggregation inhibitory activity, from the venom of the snake Bothrops asper |
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No disponible
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| Toxinological profile and histopathological alterations induced by Bothrocophias campbelli venom from Colombia |
|
2024 |
No disponible
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| Venom of the neotropical rattlesnake, Crotalus culminatus: Intraspecific variation, neutralization by antivenoms, and immunogenicity in rabbits |
|
2024 |
No disponible
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| Venomics of Leiurus abdullahbayrami, the most lethal scorpion in the Levant region of the Middle East |
|
2024 |
No disponible
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| Antibody-dependent enhancement of toxicity of myotoxin II from Bothrops asper |
|
2024 |
No disponible
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| Toxinological profile and histopathological alterations induced by Bothrocophias campbelli venom from Colombia |
|
2024 |
No disponible
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| Discovery and optimization of a broadly-neutralizing human antibody against long-chain α-neurotoxins from snakes |
|
2023 |
No disponible
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| Proteomic analysis of the mandibular glands from the Chinese crocodile lizard, Shinisaurus crocodilurus – another venomous lizard? |
|
2023 |
No disponible
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| SDS‑induced hexameric oligomerization of myotoxin‑II from Bothrops asper assessed by sedimentation velocity and nuclear magnetic resonance |
|
2023 |
No disponible
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| Virulent Brucella nosferati infecting Desmodus rotundus has emerging potential due to the broad foraging range of its bat host for humans and wild and domestic animals |
|
2023 |
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| Lys49 myotoxins, secreted phospholipase A2-like proteins of viperid venoms: a comprehensive review |
|
2023 |
No disponible
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| Stable production of recombinant SARS-CoV-2 receptor-binding domain in mammalian cells with co-expression of a fluorescent reporter and its validation as antigenic target for COVID-19 serology testing |
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2023 |
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| Skeletal muscle fiber hypercontraction induced by Bothrops asper myotoxic phospholipases A2 ex vivo does not involve a direct action on the contractile apparatus |
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2023 |
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| Antibodies against a single fraction of Micrurus dumerilii venom neutralize the lethal effect of whole venom |
|
2023 |
No disponible
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| Quantification of snake venom proteomes by mass spectrometry-considerations and perspectives. |
|
2023 |
No disponible
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| Structural basis of the myotoxic inhibition of the Bothrops pirajai PrTX-I by the synthetic varespladib |
|
2023 |
No disponible
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| Proteomic profile of the venom of three dark-colored Tityus (Scorpiones: Buthidae) from the tropical rainforests of Costa Rica |
|
2023 |
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| In vivo neutralization of Myotoxin II, a phospholipase A2 homolog from Bothrops asper venom, using peptides discovered via phage display technology |
|
2022 |
No disponible
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| Molecular architecture of the antiophidic protein DM64 and its binding specificity to myotoxin II from Bothrops asper venom |
|
2022 |
No disponible
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| Solving the microheterogeneity of Bothrops asper myotoxin-II by high-resolution mass spectrometry: insights into C-terminal region variability in Lys49-phospholipase A2 homologs |
|
2022 |
No disponible
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| In vitro discovery of a human monoclonal antibody that neutralizes lethality of cobra snake venom. |
|
2022 |
No disponible
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| Characterization of Extracellular Vesicles Secreted by a Clinical Isolate of Naegleria fowleri and Identification of Immunogenic Components within Their Protein Cargo |
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2022 |
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| Proteomic and toxicological characterization of the venoms of the most enigmatic group of rattlesnakes: The long-tailed rattlesnakes |
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2022 |
No disponible
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| Proteomic and toxicological analysis of the venom of Micrurus yatesi and its neutralization by an antivenom |
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2022 |
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| Partial efficacy of a Brazilian coralsnake antivenom and Varespladib to neutralize distinct toxic effects induced by a sublethal Micrurus dumerilii carinicauda envenoming in rats |
|
2022 |
No disponible
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| Half a century of research on Bothrops asper venom variation: biological and biomedical implications |
|
2022 |
No disponible
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| Half a century of research on Bothrops asper venom variation: biological and biomedical implications |
|
2022 |
No disponible
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| First insights into the venom composition of two Ecuadorian coral snakes |
|
2022 |
No disponible
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| In vivo treatment with varespladib, a phospholipase A2 inhibitor, prevents the peripheral neurotoxicity and systemic disorders induced by Micrurus corallinus (coralsnake) venom in rats |
|
2022 |
No disponible
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| The recovery from the neuroparalysis caused by Micrurus nigrocinctus venom is accelerated by an agonist of the CXCR4 receptor |
|
2022 |
No disponible
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| Venomics of the scorpion Tityus ocelote (Scorpiones, Buthidae): Understanding venom evolution in the subgenus Archaeotityus |
|
2022 |
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| The earless monitor lizard Lanthanotus borneensis – a venomous animal? |
|
2021 |
No disponible
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| The synthetic Varespladib molecule is a multi-functional inhibitor for PLA2 and PLA2-like ophidic toxins |
|
2021 |
No disponible
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| Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms |
|
2021 |
No disponible
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| Cardiac effect induced by Crotalus durissus cascavella venom: morphofunctional evidence and mechanism of action |
|
2021 |
No disponible
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| What’s in a mass |
|
2021 |
No disponible
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| Localization of Myotoxin I and Myotoxin II from the venom of Bothrops asper in a murine model |
|
2021 |
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| What’s in a mass |
|
2021 |
No disponible
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| Venomics of the poorly studied hognosed pitvipers Porthidium arcosae and Porthidium volcanicum |
|
2021 |
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| Cytotoxicity of snake venom Lys49 PLA2-like myotoxin on rat cardiomyocytes ex vivo does not involve a direct action on the contractile apparatus |
|
2021 |
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| Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance |
|
2021 |
No disponible
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| Antivenomics and in vivo preclinical efficacy of six Latin American antivenoms towards south-western Colombian Bothrops asper lineage venoms |
|
2021 |
No disponible
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| 12-HETE is a regulator of PGE2 production via COX-2 expression induced by a snake venom group IIA phospholipase A2 in isolated peritoneal macrophages |
|
2020 |
No disponible
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| Novel snakebite therapeutics must be tested in appropriate rescue models to robustly assess their preclinical efficacy |
|
2020 |
No disponible
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| Venom variation in Bothrops asper lineages from north-western South America. |
|
2020 |
No disponible
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| Venom variation in Bothrops asper lineages from north-western South America. |
|
2020 |
No disponible
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| Métodos de Investigación: destrezas básicas para el trabajo científico en las disciplinas biomédicas |
|
2020 |
No disponible
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| Preadipocytes are target cells for the actions of a representative gIIA phospholipase A2 which triggers proinflammatory pathways related to obesity |
|
2020 |
No disponible
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| Potent virucidal activity against Flaviviridae of a group IIA phospholipase A2 isolated from the venom of Bothrops asper |
|
2020 |
|
| Comparative biochemical characterization of Viperidae snake venoms from Perú reveals two compositional patterns of phospholipase A2 expression |
|
2020 |
No disponible
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| Functional, proteomic and transcriptomic characterization of the venom from Micrurus browni browni: identification of the first lethal multimeric neurotoxin in coral snake venom |
|
2020 |
No disponible
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| Danger in the canopy: comparative proteomics and bioactivities of the venoms of the South American palm viper Bothrops bilineatus subspecies bilineatus and smaragdinus, and antivenomics of B. b. bilineatus (Rondônia) venom against the Brazilian pentabothropic antivenom |
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2020 |
No disponible
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| Proteogenomic analysis of the Clostridium difficile exoproteome reveals a correlation between phylogenetic distribution and virulence potential |
|
2020 |
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| Development of nanobodies against hemorrhagic and myotoxic components of Bothrops atrox snake venom |
|
2020 |
No disponible
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| Venom diversity in the neotropical genus Tityus: implications for antivenom design emerging from molecular and immunochemical analyses across endemic areas of scorpionism |
|
2020 |
No disponible
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| Venomics of the Duvernoy's gland secretion of the false coral snake Rhinobothryum bovallii (Andersson, 1916) and assessment of venom lethality towards synapsid and diapsid animal models |
|
2020 |
No disponible
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| A lipidomic perspective of the action of group IIA secreted phospholipase A2 on human monocytes: lipid droplet biogenesis and activation of cytosolic phospholipase A2α |
|
2020 |
No disponible
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| Snake venomics, experimental toxic activities and clinical characteristics of human envenomation by Bothrocophias myersi (Serpentes: Viperidae) from Colombia |
|
2020 |
No disponible
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| Varespladib (LY315920) and methyl Varespladib (LY333013) abrogate or delay lethality induced by presynaptically-acting neurotoxic snake venoms |
|
2020 |
No disponible
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| Manual de Métodos Inmunológicos |
|
2020 |
No disponible
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| Ontogenetic variation in the venom of Mexican Jumping Viper (Metlapilcoatlus nummifer) |
|
2020 |
No disponible
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| Genetic and toxinological divergence among populations of Tityus trivittatus Kraepelin, 1898 (Scorpiones: Buthidae) inhabiting Paraguay and Argentina |
|
2020 |
No disponible
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| Immunological cross-recognition and neutralization studies of Micrurus mipartitus and Micrurus dumerilii venoms by two therapeutic equine antivenoms |
|
2020 |
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| Unity makes strength: exploring intra and interspecies toxin synergism between phospholipases A2 and cytotoxins |
|
2020 |
No disponible
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| Venomics of the Central American Lyre snake Trimorphodon quadruplex (Colubridae: Smith, 1941) from Costa Rica |
|
2020 |
No disponible
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| Editorial: Novel immunotherapies against envenomings by snakes and other venomous animals |
|
2020 |
No disponible
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| An interactive database for the investigation of high-density peptide microarray guided interaction patterns and antivenom cross-reactivity |
|
2020 |
No disponible
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| A secreted phospholipase A2 induces formation of smooth muscle foam cells which trans-differentiate to macrophage-like state |
|
2019 |
No disponible
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| Structural basis for phospholipase A2-like toxin inhibition by the synthetic compound Varespladib (LY315920) |
|
2019 |
|
| Isolation of two basic phospholipases A2 from Bothrops diporus snake venom: comparative characterization and synergism between Asp49 and Lys49 variants |
|
2019 |
|
| Venom characterization of the three species of Ophryacus and proteomic profiling of O. sphenophrys unveils Sphenotoxin, a novel Crotoxin-like heterodimeric β-neurotoxin |
|
2019 |
No disponible
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| New insights into the phylogeographic distribution of the 3FTx/PLA2 venom dichotomy across genus Micrurus in South America |
|
2019 |
|
| Horse immunization with short-chain consensus α-neurotoxin generates antibodies against broad spectrum of elapid venomous species |
|
2019 |
|
| First look into the venom of Roatan Island´s critically endangered coral snake Micrurus ruatanus: proteomic characterization, toxicity, immunorecognition and neutralization by an antivenom |
|
2019 |
|
| Novel three-finger toxins from Micrurus dumerilii and Micrurus mipartitus coral snake venoms: phylogenetic relationships and characterization of Clarkitoxin-I-Mdum |
|
2019 |
|
| Proteomic profiling, functional characterization, and immunoneutralization of the venom of Porthidium porrasi, a pitviper endemic to Costa Rica |
|
2019 |
|
| Biochemical characterization of the venom of Central American scorpion Didymocentrus krausi Francke, 1978 (Diplocentridae) and its toxic effects in vivo and in vitro |
|
2019 |
|
| Cloning, purification and characterization of nigrelysin, a novel actinoporin from the sea anemone Anthopleura nigrescens |
|
2019 |
No disponible
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| Neutralizing properties of Varespladib toward group I and II myotoxic phospholipases A2 |
|
2019 |
|
| Three-finger toxins from the venom of Micrurus tschudii (desert coral snake): isolation and characterization of tschuditoxin-I |
|
2019 |
|
| Venom characterization of the bark scorpion Centruroides edwardsii (Gervais 1843): composition, biochemical activities and in vivo toxicity for potential prey |
|
2019 |
|
| Enzymatic labelling of venom phospholipase A2 toxins |
|
2019 |
No disponible
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| MipLAAO, a new L-amino acid oxidase from the redtail coral snake, Micrurus mipartitus |
|
2018 |
|
| A snake venom secreted phospholipase A2 induces foam cell formation depending on the activation of factors involved in lipid homeostasis |
|
2018 |
No disponible
|
| Myotoxin-neutralizing peptides |
|
2018 |
No disponible
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| A novel pentameric phospholipase A2 myotoxin (PophPLA2) from the venom of the pit viper Porthidium ophryomegas |
|
2018 |
|
| Biological and proteolytic variation in the venom of Crotalus scutulatus scutulatus from Mexico |
|
2018 |
No disponible
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| Cell surface nucleolin interacts with and internalizes Bothrops asper Lys49 phospholipase A2 and mediates its toxic activity |
|
2018 |
|
| A myotoxic Lys49 phospholipase A2-homologue is the major component of the venom of Bothrops cotiara from Misiones, Argentina |
|
2018 |
|
| Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus |
|
2018 |
|
| Delayed oral LY333013 rescues mice from highly neurotoxic, lethal doses of Papuan Taipan (Oxyuranus scutellatus) venom |
|
2018 |
No disponible
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| Pros and cons of different therapeutic antibody formats for recombinant antivenom development |
|
2018 |
No disponible
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| Nociones de Inmunologia |
|
2018 |
No disponible
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| Innovative immunization strategies for antivenom development |
|
2018 |
No disponible
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| Unresolved issues in the understanding of the pathogenesis of local tissue damage induced by snake venoms |
|
2018 |
No disponible
|
| Intravascular hemolysis induced by phospholipases A2 from the venom of the Eastern coral snake, Micrurus fulvius: functional profile of hemolytic and non-hemolytic isoforms |
|
2018 |
|
| Depletion of complement enhances the clearance of Brucella abortus in mice |
|
2018 |
|
| In vivo neutralization of the dendrotoxin-mediated neurotoxicity of black mamba venom by oligoclonal human IgG monoclonal antibodies |
|
2018 |
No disponible
|
| Pitfalls to avoid when using phage display for snake toxins |
|
2017 |
No disponible
|
| Comparison of biochemical and cytotoxic activities of extracts obtained from dorsal spines and caudal fin of adult and juvenile non-native Caribbean lionfish (Pterois volitans/miles) |
|
2017 |
|
| Proteoform-resolved quantitative venomics: looking through a crystal ball |
|
2017 |
No disponible
|
| Crystal structure of a phospholipase A2 from Bothrops asper venom: Insights into a new putative “myotoxic cluster” |
|
2017 |
No disponible
|
| Proteomic analysis of venom variability and ontogeny across the arboreal palm-pitvipers (genus Bothriechis) |
|
2017 |
No disponible
|
| Geographical variability of the venoms of four populations of Bothrops asper from Panama: Toxicological analysis and neutralization by a polyvalent antivenom |
|
2017 |
No disponible
|
| Exploring the venom of the forest cobra snake: Toxicovenomics and antivenom profiling of Naja melanoleuca |
|
2017 |
No disponible
|
| Physicochemical characterization of Jicaro seeds (Crescentia alata H.B.K.): a novel protein-rich and oleaginous seed |
|
2017 |
No disponible
|
| Articular inflammation induced by an enzymatically-inactive Lys49 phospholipase A2: activation of endogenous phospholipases contributes to the pronociceptive effect |
|
2017 |
No disponible
|
| Exploration of immunoglobulin transcriptomes from mice immunized with three-finger toxins and phospholipases A2 from the Central American coral snake, Micrurus nigrocinctus |
|
2017 |
No disponible
|
| Strategies in 'snake venomics' aiming at an integrative view of compositional, functional, and immunological characteristics of venoms |
|
2017 |
No disponible
|
| Screening for target toxins of the antiophidic protein DM64 through a gel-based interactomics approach |
|
2017 |
No disponible
|
| Primary structures and partial toxicological characterization of two phospholipases A2 from Micrurus mipartitus and Micrurus dumerilii coral snake venoms |
|
2017 |
|
| Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead |
|
2017 |
No disponible
|
| High-density peptide microarray exploration of the antibody response in a rabbit immunized with a neurotoxic venom fraction |
|
2017 |
No disponible
|
| Cross-recognition of a pit viper (Crotalinae) polyspecific antivenom explored through high-density peptide microarray epitope mapping |
|
2017 |
No disponible
|
| Venoms of Micrurus coral snakes: evolutionary trends in compositional patterns emerging from proteomic analyses |
|
2016 |
|
| From Fangs to Pharmacology: The Future of Snakebite Envenoming Therapy |
|
2016 |
No disponible
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| N-terminal peptide of myotoxin II from Bothrops asper venom enhances the activity of endothelin converting enzyme and neprilysin |
|
2016 |
No disponible
|
| High-throughput immuno-profiling of mamba (Dendroaspis) venom toxin epitopes using high-density peptide microarrays |
|
2016 |
No disponible
|
| Venomic analysis of the poorly studied desert coral snake, Micrurus tschudii tschudii, supports the 3FTx/PLA2 dichotomy across Micrurus venoms |
|
2016 |
No disponible
|
| Integrative characterization of the venom of the coral snake Micrurus dumerilii (Elapidae) from Colombia: proteome, toxicity, and cross-neutralization by antivenom |
|
2016 |
|
| Toxicovenomics and antivenom profiling of the Eastern green mamba snake (Dendroaspis angusticeps). |
|
2016 |
No disponible
|
| Venom of the Coral Snake Micrurus clarki: Proteomic Profile, Toxicity, Immunological Cross-Neutralization, and Characterization of a Three-Finger Toxin |
|
2016 |
No disponible
|
| N-Formyl-Perosamine Surface Homopolysaccharides Hinder the Recognition of Brucella abortus by Mouse Neutrophils |
|
2016 |
No disponible
|
| Novel catalytically-inactive PII metalloproteinases from a viperid snake venom with substitutions in the canonical zinc-binding motif |
|
2016 |
|
| Mecanismo de açao dos venenos de cobras corais |
|
2016 |
No disponible
|
| Lemnitoxin, the major component of Micrurus lemniscatus coral snake venom, is a myotoxic and pro-inflammatory phospholipase A2 |
|
2016 |
No disponible
|
| Divergent functional profiles of acidic and basic phospholipases A2 in the venom of the snake Porthidium lansbergii lansbergii |
|
2016 |
|
| Characterization of a novel snake venom component: Kazal-type inhibitor-like protein from the arboreal pitviper Bothriechis schlegelii |
|
2016 |
No disponible
|
| Actividad letal de seis venenos de serpientes de importancia médica en el Ecuador |
|
2016 |
No disponible
|
| Índices bibliométricos y revistas de ‘corriente central’: implicaciones para el desarrollo de las ciencias naturales en Costa Rica |
|
2015 |
No disponible
|
| First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis |
|
2015 |
|
| Phospholipases a2 from Viperidae snakes: Differences in membranotropic activity between enzymatically active toxin and its inactive isoforms |
|
2015 |
No disponible
|
| Unveiling the nature of black mamba (Dendroaspis polylepis) venom through venomics and antivenom immunoprofiling: identification of key toxin targets for antivenom development. |
|
2015 |
No disponible
|
| A constant area monolayer method to assess optimal lipid packing for lipolysis tested with several secreted phospholipases A2 |
|
2015 |
|
| Proteomic and functional analysis of the venom of Porthidium lansbergii lansbergii (Lansberg’s hognose viper) from the Atlantic Department of Colombia |
|
2015 |
No disponible
|
| Proteomic and functional analysis of the venom of Porthidium lansbergii lansbergii (Lansberg’s hognose viper) from the Atlantic Department of Colombia |
|
2015 |
No disponible
|
| Snake venomics of monocled cobra (Naja kaouthia) and investigation of human IgG response against venom toxins |
|
2015 |
No disponible
|
| A bright future for integrative venomics |
|
2015 |
No disponible
|
| Snake venomics of Micrurus alleni and Micrurus mosquitensis from the Caribbean region of Costa Rica reveals two divergent compositional patterns in New World elapids |
|
2015 |
No disponible
|
| Phospholipase A2 enhances the endothelial cell detachment effect of a snake venom metalloproteinase in the absence of catalysis |
|
2015 |
|
| Danger in the reef: Proteome, toxicity, and neutralization of the venom of the olive sea snake, Aipysurus laevis |
|
2015 |
No disponible
|
| Antivenomics: a proteomics tool for studying the immunoreactivity of antivenoms |
|
2015 |
|
| Group-II phospholipase A2 enzymes |
|
2015 |
No disponible
|
| Selecting key toxins for focused development of elapid snake antivenoms and inhibitors guided by a Toxicity Score |
|
2015 |
No disponible
|
| First crotoxin-like phospholipase A2 complex from a New World non-rattlesnake species: Nigroviriditoxin, from the arboreal Neotropical snake Bothriechis nigroviridis |
|
2015 |
|
| Immunological profile of antivenoms: preclinical analysis of the efficacy of a polyspecific antivenom through antivenomics and neutralization assays |
|
2014 |
No disponible
|
| Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo |
|
2014 |
|
| Synergism between basic Asp49 and Lys49 phospholipase A2 myotoxins of viperid snake venom in vitro and in vivo |
|
2014 |
|
| Snake venomics of Bothrops punctatus, a semi-arboreal pitviper species from Antioquia, Colombia |
|
2014 |
No disponible
|
| Venomics of new world pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon |
|
2014 |
|
| Venomics of new world pit vipers: genus-wide comparisons of venom proteomes across Agkistrodon |
|
2014 |
|
| A structure-based proposal for a comprehensive myotoxic mechanism of phospholipase A2-like proteins from viperid snake venoms |
|
2014 |
No disponible
|
| Isolation and characterization of four medium-size disintegrins from the venoms of Central American viperid snakes of the genera Atropoides, Bothrops, Cerrophidion and Crotalus |
|
2014 |
No disponible
|
| An Asp49 Phospholipase A2 from Snake Venom Induces Cyclooxygenase-2 Expression and Prostaglandin E2 Production via Activation of NF-κB, p38MAPK, and PKC in Macrophages |
|
2014 |
No disponible
|
| Two color morphs of the pelagic yellow-bellied sea snake, pelamis platura, from different locations of Costa Rica: snake venomics, toxicity, and neutralization by antivenom |
|
2014 |
|
| Two color morphs of the pelagic yellow-bellied sea snake, pelamis platura, from different locations of Costa Rica: snake venomics, toxicity, and neutralization by antivenom |
|
2014 |
|
| Proteomic and toxicological profiling of the venom of Bothrocophias campbelli, a pitviper species from Ecuador and Colombia |
|
2014 |
|
| Proteomic and toxicological profiling of the venom of Bothrocophias campbelli, a pitviper species from Ecuador and Colombia |
|
2014 |
|
| Tissue Damage and Inflammation Induced by Snake Venoms |
|
2014 |
No disponible
|
| Omics Meets Biology: Application to the Design and Preclinical Assessment of Antivenoms |
|
2014 |
No disponible
|
| Proteomic and functional profiling of the venom of Bothrops ayerbei from Cauca, Colombia, reveals striking interspecific variation with Bothrops asper venom |
|
2014 |
|
| Proteomic and functional profiling of the venom of Bothrops ayerbei from Cauca, Colombia, reveals striking interspecific variation with Bothrops asper venom |
|
2014 |
|
| Role of enzymatic activity inmuscle damage and cytotoxicity induced by Bothrops asper Asp49 phospholipase A2 myotoxins: are there additional effector mechanisms involved? |
|
2014 |
No disponible
|
| Role of enzymatic activity inmuscle damage and cytotoxicity induced by Bothrops asper Asp49 phospholipase A2 myotoxins: are there additional effector mechanisms involved? |
|
2014 |
No disponible
|
| Intravascular hemolysis induced by the venom of the Eastern coral snake, Micrurus fulvius, in a mouse model: Identification of directly hemolytic phospholipases A2 |
|
2014 |
No disponible
|
| Understanding structural and functional aspects of PII snake venom metalloproteinases: Characterization of BlatH1, a hemorrhagic dimeric enzyme from the venom of Bothriechis lateralis |
|
2014 |
No disponible
|
| Critical role of TLR2 and MyD88 for functional response of macrophages to a group IIA-Secreted phospholipase A2 from snake venom |
|
2014 |
No disponible
|
| Utilidad de los péptidos sintéticos en estudios de estructura-función e identificación de epitopos en toxinas |
|
2014 |
No disponible
|
| Venomous snakes of Costa Rica: biological and medical implications of their venom proteomic profiles analyzed through the strategy of snake venomics |
|
2014 |
|
| Comparison of venom composition and biological activities of the subspecies Crotalus lepidus lepidus, Crotalus lepidus klauberi and Crotalus lepidus morulus from Mexico |
|
2013 |
No disponible
|
| Proteomic analysis of Bothrops pirajai snake venom and characterization of BpirMP, a new P-I metalloproteinase |
|
2013 |
No disponible
|
| Intraspecies variation in the venom of the rattlesnake Crotalus simus from Mexico: Different expression of crotoxin results in highly variable toxicity in the venoms of three subspecies |
|
2013 |
No disponible
|
| A catalytically-inactive snake venom Lys49 phospholipase A2 homolog induces expression of cyclooxygenase-2 and production of prostaglandins through selected signaling pathways in macrophages |
|
2013 |
No disponible
|
| Preclinical assessment of a polyspecific antivenom against the venoms of Cerrophidion sasai, Porthidium nasutum and Porthidium ophryomegas: Insights from combined antivenomics and neutralization assays |
|
2013 |
No disponible
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| Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics |
|
2013 |
No disponible
|
| Why myotoxin-containing snake venoms possess powerful nucleotidases? |
|
2013 |
No disponible
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| Phospholipases A2: Unveiling the secrets of a functionally versatile group of snake venom toxins |
|
2013 |
No disponible
|
| Homogenates of skeletal muscle injected with snake venom inhibit myogenic differentiation in cell culture |
|
2013 |
No disponible
|
| Amino acid sequence and biological characterization of BlatPLA2, a non-toxic acidic phospholipase A2 from the venom of the arboreal snake Bothriechis lateralis from Costa Rica |
|
2013 |
|
| A Lys49 Phospholipase A2, Isolated from Bothrops asper Snake Venom, Induces Lipid Droplet Formation in Macrophages Which Depends on Distinct Signaling Pathways and the C-Terminal Region |
|
2013 |
No disponible
|
| Muscle phospholipid hydrolysis by Bothrops asper Asp49 and Lys49 phospholipase A2 myotoxins – distinct mechanisms of action |
|
2013 |
No disponible
|
| Investigación científica y tecnológica en el Instituto Clodomiro Picado: Una perspectiva bibliométrica de cuatro décadas (1970-2010) |
|
2012 |
No disponible
|
| An acidic phospholipase A2 with antibacterial activity from Porthidium nasutum snake venom |
|
2012 |
No disponible
|
| Snake venomics of the pit vipers Porthidium nasutum, Porthidium ophryomegas, and Cerrophidion godmani from Costa Rica: Toxicological and taxonomical insights |
|
2012 |
No disponible
|
| Venenos de serpiente: de la investigación al tratamiento |
|
2012 |
No disponible
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| Resurrexit, sicut dixit, alleluia. Snake venomics from a 26-years old polyacrylamide focusing gel |
|
2012 |
No disponible
|
| A Lys49-PLA2 myotoxin of Bothrops asper triggers a rapid death of macrophages that involves autocrine purinergic receptor signaling |
|
2012 |
No disponible
|
| Identification of linear B-cell epitopes on myotoxin-II, a Lys49 phospholipase A2 homologue from Bothrops asper snake venom |
|
2012 |
|
| Snake venom Lys49 myotoxins: from phospholipases A2 to non-enzymatic membrane disruptors |
|
2012 |
|
| Snake venomics and toxicological profiling of the arboreal pitviper Bothriechis supraciliaris from Costa Rica |
|
2012 |
No disponible
|
| Snake venomics of crotalus tigris: the minimalist toxin arsenal of the deadliest neartic rattlesnake venom: evolutionary clues for generating a pan-specific antivenom against crotalid type II venoms |
|
2012 |
No disponible
|
| Mipartoxin-I, a novel three-finger toxin, is the major neurotoxic component in the venom of the redtail coral snake Micrurus mipartitus (Elapidae) |
|
2012 |
|
| Isolation and biochemical, functional and structural characterization of a novel L-amino acid oxidase from Lachesis muta snake venom |
|
2012 |
No disponible
|
| Implementación de un laboratorio de análisis proteómicos en el Instituto Clodomiro Picado (UCR): primeras experiencias en Costa Rica |
|
2012 |
No disponible
|
| Envenomations by Bothrops and Crotalus Snakes Induce the Release of Mitochondrial Alarmins |
|
2012 |
No disponible
|
| Venomic and antivenomic analyses of the Central American coral snake, Micrurus nigrocinctus (Elapidae) |
|
2011 |
No disponible
|
| Proteomic and biological characterization of the venom of the redtail coral snake, Micrurus mipartitus (Elapidae), from Colombia and Costa Rica |
|
2011 |
|
| Profiling the venom gland transcriptomes of Costa Rican snakes by 454 pyrosequencing |
|
2011 |
No disponible
|
| Antivenoms for Snakebite Envenomings |
|
2011 |
No disponible
|
| Phospholipases A2 From Viperidae Snake Venoms: How do They Induce Skeletal Muscle Damage? |
|
2011 |
No disponible
|
| Snake population venomics and antivenomics of Bothrops atrox: Paedomorphism along its transamazonian dispersal and implications of geographic venom variability on snakebite management |
|
2011 |
No disponible
|
| Venenos de serpientes de la familia Viperidae en América: Bioquímica y fisiopatología. |
|
2011 |
No disponible
|
| Membrane cholesterol modulates the cytolytic mechanism of myotoxin II, a Lys49 phospholipase A2 homologue from the venom of Bothrops asper |
|
2011 |
No disponible
|
| Comparative study of the cytolytic activity of snake venoms from African spitting cobras (Naja spp., Elapidae) and its neutralization by a polyspecific antivenom |
|
2011 |
|
| A phospholipase A2 from Bothrops asper snake venom activates neutrophils in culture: Expression of cyclooxygenase-2 and PGE2 biosynthesis |
|
2011 |
No disponible
|
| Tissue pathology induced by snake venoms: How to understand a complex pattern of alterations from a systems biology perspective? |
|
2010 |
No disponible
|
| Bothrops snake myotoxins induce a large efflux of ATP and potassium with spreading of cell damage and pain |
|
2010 |
No disponible
|
| The C-terminal region of a Lys49 myotoxin mediates Ca2þ influx in C2C12 myotubes |
|
2010 |
No disponible
|
| Antivenomics of Atropoides mexicanus and Atropoides picadoi snake venoms: Relationship to the neutralization of toxic and enzymatic activities |
|
2010 |
No disponible
|
| Snake venomics of Bothriechis nigroviridis reveals extreme variability among palm pitviper venoms: different evolutionary solutions for the same trophic purpose |
|
2010 |
No disponible
|
| Snake Venomics of the Central American Rattlesnake Crotalus simus and the South American Crotalus durissus Complex Points to Neurotoxicity as an Adaptive Paedomorphic Trend along Crotalus Dispersal in South America |
|
2010 |
No disponible
|
| Isolation of an acidic phospholipase A2 from the venom of the snake Bothrops asper of Costa Rica: Biochemical and toxicological characterization |
|
2010 |
No disponible
|
| Synthetic peptides derived from the C-terminal region of Lys49 phospholipase A2 homologues from Viperidae snake venoms: biomimetic activities and potential applications |
|
2010 |
No disponible
|
| Acute physiopathological effects of honeybee (Apis mellifera) envenoming by subcutaneous route in a mouse model |
|
2010 |
No disponible
|
| Biochemistry and toxicology of toxins purified from the venom of the snake Bothrops asper |
|
2009 |
No disponible
|
| The Phospholipase A2 Homologues of Snake Venoms: Biological Activities and Their Possible Adaptive Roles |
|
2009 |
No disponible
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| Calcium imaging of muscle cells treated with snake myotoxins reveals toxin synergism and presence of acceptors |
|
2009 |
No disponible
|
| Venom, venomics, antivenomics |
|
2009 |
|
| Mortality by Hymenoptera stings in Costa Rica, 1985-2006 |
|
2009 |
No disponible
|
| Snake venomics and antivenomics of Bothrops atrox venoms from Colombia and the Amazon regions of Brazil, Perú and Ecuador suggest the occurrence of geographic variation of venom phenotype by a trend towards paedomorphism |
|
2009 |
No disponible
|
| Snake venomics and antivenomics: Proteomic tools in the design and control of antivenoms for the treatment of snakebite envenoming |
|
2009 |
No disponible
|
| Neutralization of Bothrops asper venom by antibodies, natural products, and synthetic drugs: contributions to understanding snakebite envenomings and their treatment |
|
2009 |
No disponible
|
| Técnicas de Laboratorio en Inmunología Clínica |
|
2009 |
No disponible
|
| Snake venomics of the South and Central American Bushmasters. Comparison of the toxin composition of Lachesis muta gathered from proteomic versus transcriptomic analysis |
|
2008 |
No disponible
|
| Ability of fucoidan to prevent muscle necrosis induced by snake venom myotoxins: comparison of high- and low-molecular weight fractions |
|
2008 |
|
| Human heterophilic antibodies against equine immunoglobulins: assessment of their role in the early adverse reactions to antivenom administration |
|
2008 |
|
| Snake Venomics of the Lesser Antillean Pit Vipers Bothrops caribbaeus and Bothrops lanceolatus: Correlation with Toxicological Activities and Immunoreactivity of a Heterologous Antivenom |
|
2008 |
No disponible
|
| Catalytically inactive phospholipase A2 homologue binds to vascular endothelial growth factor receptor-2 via C-terminal loop region |
|
2008 |
No disponible
|
| Systemic and local myotoxicity induced by snake venom group II phospholipases A2: Comparison between crotoxin, crotoxin B and a Lys49 PLA2 homologue |
|
2008 |
No disponible
|
| Computational Biology in Costa Rica: the role of a small country in the global context of bioinformatics |
|
2008 |
No disponible
|
| Susceptibilidad de Trypanosoma cruzi a diferentes venenos de serpientes de Costa Rica |
|
2008 |
No disponible
|
| Snake Venomics and Antivenomics of the Arboreal Neotropical Pitvipers Bothriechis lateralis and Bothriechis schlegelii |
|
2008 |
No disponible
|
| Effects of Bothrops asper snake venom on lymphatic vessels: insights into a hidden aspect of envenomation |
|
2008 |
|
| Snake Venomics of Central American Pitvipers: Clues for Rationalizing the Distinct Envenomation Profiles of Atropoides nummifer and Atropoides picadoi |
|
2008 |
No disponible
|
| Cellular pathology induced by snake venom phospholipase A2 myotoxins and neurotoxins: common aspects of their mechanisms of action |
|
2008 |
No disponible
|
| Fungicidal activity of a phospholipase A2-derived synthetic peptide variant against Candida albicans |
|
2007 |
No disponible
|
| Structural and functional properties of BaTX, a new Lys49 phospholipase A2 homologue isolated from the venom of the snake Bothrops alternatus |
|
2007 |
No disponible
|
| Antitumor effects of cationic synthetic peptides derived from Lys49 phospholipase A2 homologues of snake venoms |
|
2007 |
No disponible
|
| Isolation, characterization and molecular cloning of AnMIP, a new α-type phospholipase A2 myotoxin inhibitor from the plasma of the snake Atropoides nummifer (Viperidae: Crotalinae) |
|
2007 |
|
| Cytotoxicity induced in myotubes by a Lys49 phospholipase A2 homologue from the venom of the snake Bothrops asper: Evidence of rapid plasma membrane damage and a dual role for extracellular calcium |
|
2007 |
No disponible
|
| Cytotoxicity of Lachesis muta muta snake (bushmaster) venom and its purified basic phospholipase A2 (LmTX-I) in cultured cells |
|
2007 |
No disponible
|
| Trends in Snakebite Envenomation Therapy: Scientific, Technological and Public Health Considerations |
|
2007 |
No disponible
|
| Anti-human erythrocyte antibodies in horse-derived antivenoms used in the treatment of snakebite envenomations |
|
2007 |
No disponible
|
| Effect of calcineurin inhibitors on myotoxic activity of crotoxin and Bothrops asper phospholipase A2 myotoxins in vivo and in vitro |
|
2006 |
No disponible
|
| Structure of myotoxin-II, a catalytically inactive Lys49 phospholipase A2 homologue from Atropoides nummifer venom |
|
2006 |
No disponible
|
| Neurotoxicity and other pharmacological activities of the snake venom phospholipase A2 OS2: the N-terminal region is more important than enzymatic activity |
|
2006 |
No disponible
|
| Biological and structural characterization of crotoxin and new isoform of crotoxin B PLA2 (F6a) from Crotalus durissus collilineatus snake venom |
|
2006 |
No disponible
|
| Pharmacokinetics of whole IgG equine antivenom: comparison between normal and envenomed rabbits |
|
2006 |
No disponible
|
| Differential susceptibility of C2C12 myoblasts and myotubes to group II phospholipase A2 myotoxins from crotalid snake venoms |
|
2005 |
|
| Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs |
|
2005 |
|
| Anticomplementary activity of equine whole IgG antivenoms: comparison of three fractionation protocols |
|
2005 |
|
| Inhibitory effects of Piper umbellatum and Piper peltatum extracts towards myotoxic phospholipases A2 from Bothrops snake venoms: isolation of 4-nerolidylcatechol as active principle |
|
2005 |
|
| Myotoxic and cytolytic activities of dimeric Lys49 phospholipase A2 homologues are reduced, but not abolished, by a pH-induced dissociation |
|
2005 |
No disponible
|
| Antimicrobial activity of myotoxic phospholipases A2 from crotalid snake venoms and synthetic peptide variants derived from their C-terminal region |
|
2005 |
|
| Bactericidal and anti-endotoxic properties of short cationic peptides derived from a snake venom Lys49 phospholipase A2 |
|
2005 |
No disponible
|
| Activation of cellular functions in macrophages by venom secretory Asp-49 and Lys-49 phospholipases A2 |
|
2005 |
No disponible
|
| Neutralization of four Peruvian Bothrops sp. snake venoms by polyvalent antivenoms produced in Perú and Costa Rica: preclinical assessment |
|
2005 |
|
| Inhibition of Myotoxic Activity of Bothrops asper Myotoxin II by the Anti-trypanosomal Drug Suramin |
|
2005 |
No disponible
|
| Medicinal plants with inhibitory properties against snake venoms |
|
2005 |
No disponible
|
| A Lys49 phospholipase A2 homologue from Bothrops asper snake venom induces proliferation, apoptosis and necrosis in a lymphoblastoid cell line |
|
2005 |
No disponible
|
| Snake venom phospholipase A2s (Asp49 and Lys49) induce mechanical allodynia upon peri-sciatic administration: involvement of spinal cord glia, proinflammatory cytokines and nitric oxide |
|
2004 |
No disponible
|
| Crystallization of the Lys49 PLA2 homologue, myotoxin II from the venom of Atropoides nummifer |
|
2004 |
No disponible
|
| Structural and functional characterization of myotoxin I, a Lys49 phospholipase A2 homologue from the venom of the snake Bothrops atrox |
|
2004 |
|
| Effect of a recombinant Lys49 PLA2 myotoxin and Lys49 PLA2-derived synthetic peptides from Agkistrodon species on membrane permeability to water. |
|
2004 |
No disponible
|
| Inhibitory effect of fucoidan on the activities of crotaline snake venom myotoxic phospholipases A2 |
|
2003 |
No disponible
|
| Comparative study of synthetic peptides corresponding to region 115-129 in Lys49 myotoxic phospholipases A2 from snake venoms |
|
2003 |
No disponible
|
| Efectos locales en el envenenamiento ofídico en América Latina |
|
2003 |
No disponible
|
| Pharmacokinetic-pharmacodynamic relationships of immunoglobulin therapy for envenomation. |
|
2003 |
No disponible
|
| An overview of Lysine-49 phospholipase A2 myotoxins from crotalid snake venoms and their structural determinants of myotoxic action |
|
2003 |
No disponible
|
| Hyperalgesia induced by Asp49 and Lys49 phospholipases A2 from Bothrops asper snake venom: pharmacological mediation and molecular determinants |
|
2003 |
No disponible
|
| Structural characterization and phylogenetic relationships of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a Lys49 phospholipase A2 homologue |
|
2002 |
No disponible
|
| Functional analysis of DM64, an antimyotoxic protein with immunoglobulin-like structure from Didelphis marsupialis serum |
|
2002 |
No disponible
|
| Hemostatic effects induced by Thalassophryne nattereri fish venom: a model of endothelium-mediated blood flow impairment. |
|
2002 |
No disponible
|
| Skeletal muscle necrosis and regeneration after injection of Thalassophryne nattereri (niquim) fish venom in mice |
|
2001 |
No disponible
|
| The venom of Bothrops asper from Guatemala: toxic activities and neutralization by antivenoms |
|
2001 |
|
| Serum antibody response to polysaccharides in children with recurrent respiratory tract infections |
|
2001 |
No disponible
|
| Immunochemical properties of the N-terminal helix of myotoxin II, a lysine-49 phospholipase A2 from Bothrops asper snake venom |
|
2001 |
No disponible
|
| Identification of the myotoxic site of the Lys49 phospholipase A2 from Agkistrodon piscivorus piscivorus snake venom: synthetic C-terminal peptides from Lys49, but not from Asp49 myotoxins, exert membrane-damaging activities |
|
2001 |
No disponible
|
| Systemic cytokine response in children bitten by snakes in Costa Rica |
|
2001 |
No disponible
|
| Peligros de los falsos positivos en la determinación de gonadotropina coriónica |
|
2001 |
No disponible
|
| Venom of the crotaline snake Atropoides nummifer (jumping viper) from Guatemala and Honduras: comparative toxicological characterization, isolation of a myotoxic phospholipase A(2) homologue and neutralization by two antivenoms |
|
2001 |
|
| Comparison between IgG and F(ab′)2 polyvalent antivenoms: neutralization of systemic effects induced by Bothrops asper venom in mice, extravasation to muscle tissue, and potential for induction of adverse reactions |
|
2001 |
|
| Comparative study on the ability of IgG and Fab sheep antivenoms to neutralize local hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom |
|
2000 |
|
| Desarrollo científico en Costa Rica: un análisis bibliométrico a través del Science Citation Index durante el periodo 1980-1998 |
|
2000 |
No disponible
|
| Structural and functional characterization of BnSP-7, a lysine-49 myotoxic phospholipase A2 homologue from Bothrops neuwiedi pauloensis venom |
|
2000 |
No disponible
|
| Identification of residues critical for toxicity in Clostridium perfringens phospholipase C, the key toxin in gas gangrene |
|
2000 |
|
| Isolation and characterization of myotoxin II from Atropoides (Bothrops) nummifer snake venom, a new Lys49 phospholipase A2 homologu |
|
2000 |
No disponible
|
| Two phospholipase A2 inhibitors from the plasma of Cerrophidion (Bothrops) godmani which selectively inhibit two different group-II phospholipase A2 myotoxins from its own venom: isolation, molecular cloning and biological properties |
|
2000 |
|
| Myotoxic phospholipases A2 in Bothrops snake venoms: Effect of chemical modifications on the enzymatic and pharmacological properties of bothropstoxins from Bothrops jararacussu |
|
2000 |
No disponible
|
| Structural and functional characterization of myotoxin I, a Lys49 phospholipase A(2) homologue from Bothrops moojeni (Caissaca) snake venom |
|
2000 |
No disponible
|
| Tyr→Trp-substituted peptide 115-129 of a Lys49 phospholipase A2 expresses enhanced membrane-damaging activities and reproduces its in vivo myotoxic effect |
|
1999 |
No disponible
|
| Characterization of a basic phospholipase A2-homologue myotoxin isolated from the venom of the snake Bothrops neuwiedii (yarará chica) from Argentina |
|
1999 |
No disponible
|
| Universidad de Costa Rica: liderazgo en producción científica de nivel internacional, 1980-1998. |
|
1999 |
No disponible
|
| Inhibition of the myotoxic activity of Bothrops aspermyotoxin II in mice by immunization with its synthetic 13-mer peptide 115-129 |
|
1999 |
|
| Bases moleculares del reconocimiento de antígenos |
|
1999 |
No disponible
|
| Comparative study of the cytolytic activity of myotoxic phospholipases A2 on mouse endothelial (tEnd) and skeletal muscle (C2C12) cells in vitro |
|
1999 |
No disponible
|
| Neutralization of local tissue damage induced by Bothrops asper (terciopelo) snake venom |
|
1998 |
|
| Immunochemical characterization and role in toxic activities of region 115-129 of myotoxin II, a Lys49 phospholipase A2 from Bothrops asper snake venom |
|
1998 |
|
| Bactericidal activity of Lys49 and Asp49 myotoxic phospholipases A2 from Bothrops asper snake venom: synthetic Lys49 myotoxin II-(115-129)-peptide identifies its bactericidal region |
|
1998 |
No disponible
|
| Biochemical characterization and pharmacological properties of a phospholipase A2 myotoxin inhibitor from the plasma of the snake Bothrops asper |
|
1997 |
|
| Isolation and characterization of a myotoxic phospholipase A2 from the venom of the arboreal snake Bothriechis (Bothrops) schlegelii from Costa Rica |
|
1997 |
No disponible
|
| Immunoglobulin G and F(ab')2 polyvalent antivenoms do not differ in their ability to neutralize hemorrhage, edema and myonecrosis induced by Bothrops asper (terciopelo) snake venom |
|
1997 |
No disponible
|
| Development of immunoassays for determination of circulating venom antigens during envenomations by coral snakes (Micrurus species) |
|
1997 |
No disponible
|
| Lys-49 phospholipases A2 as active enzymes for beta-arachidonoyl phospholipid bilayer membranes |
|
1997 |
No disponible
|
| Evaluation of the neutralizing ability of antivenoms for the treatment of snake bite envenoming in Central America |
|
1996 |
No disponible
|
| Neutralization of myonecrosis, hemorrhage, and edema induced by Bothrops asper snake venom by homologous and heterologous pre-existing antibodies in mice |
|
1996 |
No disponible
|
| Similar effectiveness of Fab and F(ab')2 antivenoms in the neutralization of hemorrhagic activity of Vipera berus snake venom in mice |
|
1996 |
No disponible
|
| Las citokinas, elementos centrales para la comprensión y manipulación terapéutica del sistema inmune (Parte II) |
|
1996 |
No disponible
|
| Acute-phase reactions, including cytokines, in patients bitten by Bothrops and Crotalus snakes in Brazil |
|
1995 |
No disponible
|
| Phospholipase A2 and inflammation |
|
1995 |
No disponible
|
| Evaluación de la capacidad de cuatro antivenenos comerciales para neutralizar el veneno de la serpiente Bothrops asper (terciopelo) de Costa Rica |
|
1995 |
No disponible
|
| Antibodies to Helicobacter pylori in dyspeptic patients, asymptomatic adults, and children from Costa Rica |
|
1995 |
No disponible
|
| Local tissue damage induced by BaP1, a metalloproteinase isolated from Bothrops asper (Terciopelo) snake venom |
|
1995 |
No disponible
|
| Las citokinas, elementos centrales para la comprensión y manipulación terapéutica del sistema inmune (Parte 1) |
|
1995 |
No disponible
|
| Autocatalytic acylation of phospholipase-like myotoxins |
|
1995 |
No disponible
|
| Phospholipase A2 myotoxins from Bothrops snake venoms |
|
1995 |
No disponible
|
| Purification and characterization of myotoxin IV, a phospholipase A2 variant, from Bothrops asper snake venom |
|
1995 |
No disponible
|
| Phospholipase A2 myotoxins from Bothrops snake venoms [Artículo de revisión] |
|
1995 |
No disponible
|
| Broad cytolytic specificity of myotoxin II, a lysine-49 phospholipase A2 of Bothrops asper snake venom |
|
1994 |
No disponible
|
| Neutralizing interaction between heparins and myotoxin II, a Lys-49 phospholipase A2 from Bothrops asper snake venom. Identification of a heparin-binding and cytolytic toxin region by the use of synthetic peptides and molecular modeling |
|
1994 |
No disponible
|
| Cleavage of the NH2-Terminal Octapeptide of Bothrops asper Myotoxic Lysine-49 Phospholipase A2 Reduces Its Membrane-Destabilizing Effect |
|
1994 |
No disponible
|
| The dynamics of local tissue damage induced by Bothrops asper snake venom and myotoxin II on the mouse cremaster muscle: an intravital and electron microscopic study |
|
1994 |
No disponible
|
| Effect of various Viperidae and Crotalidae snake venoms on endothelial cells in vitro |
|
1994 |
No disponible
|
| Neutralization of the cytolytic and myotoxic activities of phospholipases A2 from Bothrops asper snake venom by glycosaminoglycans of the heparin/heparan sulfate family |
|
1994 |
No disponible
|
| Immunochemical characterization of Micrurus nigrocinctus nigrocinctus venom with monoclonal and polyclonal antibodies |
|
1994 |
No disponible
|
| Activity of hemorrhagic metalloproteinase BaH-1 and myotoxin II from Bothrops asper snake venom on capillary endothelial cells in vitro |
|
1994 |
No disponible
|
| Electrophoretic and immunochemical studies of Micrurus venoms |
|
1994 |
No disponible
|
| p-Bromophenacyl bromide modification of Bothrops asper myotoxin II, a lysine-49 phospholipase A2, affects its pharmacological activities |
|
1993 |
No disponible
|
| Host response to Bothrops asper snake venom: analysis of edema formation, inflammatory cells, and cytokine release in a mouse model |
|
1993 |
No disponible
|
| An MTT-based method for the in vivo quantification of myotoxic activity of snake venoms and its neutralization by antibodies |
|
1993 |
No disponible
|
| Biological and biochemical activities of Vipera berus (European viper) venom |
|
1993 |
No disponible
|
| Immunoenzymatic quantitation of antibodies to Bothrops asper myotoxins after polyvalent antivenom administration in mice. |
|
1992 |
No disponible
|
| Individual expression patterns of myotoxin isoforms in the venom of the snake Bothrops Asper. |
|
1992 |
No disponible
|
| Neutralization of myotoxic phospholipases A2 from the venom of the snake Bothrops asper by monoclonal antibodies |
|
1992 |
No disponible
|
| Isolation and characterization of basic myotoxic phospholipases A2 from Bothrops godmani (Godman's pit viper) snake venom |
|
1992 |
No disponible
|
| An electrophoretic study on phospholipase A2 isoenzymes in the venoms of Central American crotaline snakes |
|
1992 |
No disponible
|
| Quantitation by enzyme-immunoassay of antibodies against Bothrops myotoxins in four commercially-available antivenoms |
|
1991 |
No disponible
|
| Myotoxin II from Bothrops asper (Terciopelo) venom is a lysine-49 phospholipase A2 |
|
1991 |
No disponible
|
| The effect of myotoxins isolated from Bothrops snake venoms on multilamellar liposomes: relationship to phospholipase A2, anticoagulant and myotoxic activities |
|
1991 |
No disponible
|
| Determinación inmunoenzimática de los niveles séricos de inmunoglobina E en niños asmáticos de la Meseta Central de Costa Rica |
|
1991 |
No disponible
|
| Neutralization of coral snake Micrurus nigrocinctus venom by a monovalent antivenom |
|
1991 |
No disponible
|
| Dissociation of enzymatic and toxic activities by the use of antibodies |
|
1990 |
No disponible
|
| Effect of storage temperature on the stability of polyvalent antivenom produced in Costa Rica. |
|
1990 |
No disponible
|
| Isolation of basic myotoxins from Bothrops Moojeni and Bothrops Atrox snake venoms |
|
1990 |
No disponible
|
| Standardization of assays for testing the neutralizing ability of antivenoms |
|
1990 |
No disponible
|
| Ontogenetic changes in the venom of the snake Lachesis muta stenophrys (bushmaster) from Costa Rica |
|
1990 |
No disponible
|
| South American snake venom proteins antigenically-related to Bothrops asper myotoxins. |
|
1990 |
No disponible
|
| Equine antibodies to Bothrops asper myotoxin II: isolation from polyvalent antivenom and neutralizing ability. |
|
1990 |
No disponible
|
| Isolation of a galactose-binding lectin from the venom of the snake Bothrops godmani (Godmann's pit viper). |
|
1990 |
No disponible
|
| A new muscle damaging toxin, myotoxin II, from the venom of the snake Bothrops asper (terciopelo) |
|
1989 |
No disponible
|
| Myonecrosis induced in mice by a basic myotoxin isolated from the venom of the snake Bothrops nummifer (jumping viper) from Costa Rica |
|
1989 |
No disponible
|
| Local tissue damage induced by Bothrops snake venoms - A review |
|
1989 |
No disponible
|
| Efecto del suero antiofídico sobre la actividad hemolítica del complemento humano (in vitro) y de conejo (in vitro e in vivo). |
|
1989 |
No disponible
|
| Histopathological and biochemical alterations induced by intramuscular injection of Bothrops asper (terciopelo) venom in mice |
|
1989 |
No disponible
|
| El suero de neonatos de Clelia clelia (Serpentes: Colubridae) neutraliza la acción hemorrágica del veneno de Bothrops asper (Serpentes: Viperidae). |
|
1989 |
No disponible
|
| Production and partial characterization of monoclonal antibodies to Bothrops asper (terciopelo) myotoxin |
|
1988 |
No disponible
|
| El suero antiofídico polivalente producido en Costa Rica: Estabilidad y capacidad neutralizante |
|
1988 |
No disponible
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| Effects of a myotoxic phospholipase A2 isolated from Bothrops asper venom on skeletal muscle sarcoplasmic reticulum |
|
1987 |
No disponible
|
| Detection of proteins antigenically-related to Bothrops asper myotoxin in crotaline snake venoms |
|
1987 |
No disponible
|
| Immunohistochemical demonstration of the binding of bothrops asper myotoxin to skeletal muscle sarcolemma |
|
1987 |
No disponible
|
| Antibody neutralization of a myotoxin from the venom of Bothrops asper (terciopelo) |
|
1987 |
No disponible
|
| Isolation and partial characterization of a myotoxin from the venom of the snake Bothrops nummifer |
|
1986 |
No disponible
|
| Comparative study of the edema-forming activity of Costa Rican snake venoms and its neutralization by a polyvalent antivenom |
|
1986 |
No disponible
|
| Pharmacological activities of a toxic phospholipase A isolated from the venom of the snake Bothrops asper |
|
1986 |
No disponible
|
| Cálculo de la actividad hemolítica del complemento sérico (CH50) mediante un programa en "BASIC": Comparación con el método gráfico manual. |
|
1986 |
No disponible
|
| Determinación cuantitativa de la actividad lítica del complemento sérico (CH50) en adultos costarricenses |
|
1986 |
No disponible
|
| Pathogenesis of myonecrosis induced by coral snake (Micrurus nigrocinctus) venom in mice |
|
1986 |
No disponible
|
| Cambios en el patrón electroforético del veneno de cascabela muda (Lachesis muta stenophrys) durante el almacenamiento bajo diferentes condiciones |
|
1985 |
No disponible
|
| Niveles de inmunoglobulinas séricas (IgG, IgA e IgM) en adultos jóvenes sanos, por el método de inmunodifusión radial |
|
1985 |
No disponible
|
| Edema-forming activity of bushmaster (Lachesis muta stenophrys) and Central American rattlesnake (Crotalus durissus durissus) venoms and neutralization by a polyvalent antivenom |
|
1985 |
No disponible
|
| Isolation from a polyvalent antivenom of antibodies to a myotoxin in Bothrops asper snake venom |
|
1985 |
|
| Porcentaje y cifra absoluta de linfocitos T en sangre periférica por el método de rosetas E: estudio de cuarenta adultos sanos |
|
1985 |
No disponible
|
| Producción de placas de inmunodifusión radial para la cuantificación de IgG humana |
|
1985 |
No disponible
|
| Estudio comparativo de los venenos de serpiente Cascabel (Crotalus durissus durissus) de ejemplares adultos y recien nacidos |
|
1983 |
No disponible
|
| Local effects induced by coral snake venoms: Evidence of myonecrosis after experimental inoculations of venoms from five species |
|
1983 |
No disponible
|
| La actividad proteolítica de los venenos de serpientes de Costa Rica sobre la caseína |
|
1983 |
No disponible
|
| Patogénesis y neutralización de los efectos locales inducidos por el veneno de la serpiente "terciopelo" (Bothrops asper). |
|
1982 |
No disponible
|
| Estudio de la capacidad ofiófaga y la resistencia de la zopilota (Clelia clelia, Colubridae) de Costa Rica a los venenos de serpiente |
|
1982 |
No disponible
|
| Neutralization of local effects of the terciopelo (Bothrops asper) venom by blood serum of the colubrid snake Clelia clelia |
|
1982 |
No disponible
|
| Anemias hemolíticas por autoinmunidad y por mecanismos inmunes inducidos por medicamentos |
|
1981 |
No disponible
|
