Investigador(a)

Alvaro Segura Ruiz

  • Correo electrónico: ALVARO.SEGURARUIZ@ucr.ac.cr
  • Categoría Regimen Académico: PROF. INTERINO LIC.
  • Grado Académico: MAG.
  • Unidad Base: INSTITUTO CLODOMIRO PICADO

Proyectos

Mostrando 0 proyectos

Núm. de proyecto Descripción Unidad de Investigación

Distinciones

Distinción Año Entidad Ámbito Descripción
OTRA DISTINCION 2009 Universidad De Costa Rica NACIONAL DISTINCIÓN ANUAL ADMINIS. GRUPAL

BECAS

País Entidad Año de inicio Año de término Descripción
No hay datos disponibles

Publicaciones

Mostrando 40 publicaciones

TÍTULO TIPO FECHA PROYECTO
In vitro Characterization of Anti-SARS-CoV-2 Intravenous Immunoglobulins (IVIg) Produced From Plasma of Donors Immunized With the BNT162b2 Vaccine and Its Comparison With a Similar Formulation Produced From Plasma of COVID-19 Convalescent Donors
  • artículo original
2022
High Efficacy of Therapeutic Equine Hyperimmune Antibodies Against SARS-CoV-2 Variants of Concern
  • artículo original
2021
Heterologous hyperimmune polyclonal antibodies against SARS-COV-2: A broad coverage, affordable, and scalable potential immunotherapy for Covid-19
  • artículo original
2021
Proteomic and toxinological characterization of the venom of the South African Ringhals cobra Hemachatus haemachatus
  • artículo original
2018
Preclinical evaluation of the efficacy of antivenoms for snakebite envenoming: State-of-the-art and challenges ahead
  • artículo original
2017

No disponible

Comparison of the adjuvant activity of emulsions with different physicochemical properties on the antibody response towards the venom of West African carpet viper (Echis ocellatus)
  • artículo original
2017
Pathogenesis of dermonecrosis induced by venom of the spitting cobra, Naja nigricollis: An experimental study in mice
  • artículo original
2016

No disponible

Neutralization of the neuromuscular inhibition of venom and taipoxin from the taipan (Oxyuranus scutellatus) by F(ab0)2 and whole IgG antivenoms
  • artículo original
2016

No disponible

Development of a chicken-derived antivenom against the taipan snake (Oxyuranus scutellatus) venom and comparison with an equine antivenom
  • artículo original
2016

No disponible

Purification of equine whole IgG snake antivenom by using an aqueous two phase system as a primary purification step
  • artículo original
2015
Effect of geographical variation of Echis ocellatus, Naja nigricollis and Bitis arietans venoms on their neutralization by homologous and heterologous antivenoms
  • artículo original
2015

No disponible

Lachesis stenophrys venom reduces the equine antibody response towards Bothrops asper venom used as co-immunogen in the production of polyspecific snake antivenom
  • artículo original
2015
Industrial Production and Quality Control of Snake Antivenoms
  • capítulo de libro
2014

No disponible

Toxicity of Bothrops sp snake venoms from Ecuador and preclinical assessment of the neutralizing efficacy of a polyspecific antivenom from Costa Rica
  • artículo original
2014

No disponible

Freeze-dried snake antivenoms formulated with sorbitol, sucrose or mannitol: Comparison of their stability in an accelerated test
  • artículo original
2014

No disponible

Antivenomic Characterization of Two Antivenoms Against the Venom of the Taipan, Oxyuranus scutellatus, from Papua New Guinea and Australia
  • artículo original
2014

No disponible

Pathogenic mechanisms underlying adverse reactions induced by intravenous administration of snake antivenoms
  • artículo original
2013

No disponible

Assessing the preclinical efficacy of antivenoms: From the lethality neutralization assay to antivenomics
  • artículo original
2013

No disponible

Role of the animal model on the pharmacokinetics of equine-derived antivenoms
  • artículo original
2013

No disponible

Comparative proteomic analysis of the venom of the taipan snake, Oxyuranus scutellatus, from Papua New Guinea and Australia: Role of neurotoxic and procoagulant effects in venom toxicity
  • artículo original
2012

No disponible

Low pH formulation of whole IgG antivenom: Impact on quality, safety, neutralizing potency and viral inactivation
  • artículo original
2012

No disponible

Comparative study of the efficacy and safety of two polyvalent, caprylic acid fractionated [IgG and F(ab0)2] antivenoms, in Bothrops asper bites in Colombia
  • artículo original
2012

No disponible

Snake venomics and antivenomics of Protobothrops mucrosquamatus and Viridovipera stejnegeri from Taiwan: Keys to understand the variable immune response in horses
  • artículo original
2012

No disponible

Venom of Bothrops asper from Mexico and Costa Rica: Intraspecific variation and cross-neutralization by antivenoms
  • artículo original
2012
Purification of IgG and albumin from human plasma by aqueous two phase system fractionation
  • artículo original
2012

No disponible

Comparison of the effect of Crotalus simus and Crotalus durissus ruruima venoms on the equine antibody response towards Bothrops asper venom: Implications for the production of polyspecific snake antivenoms
  • artículo original
2011
Preclinical evaluation of caprylic-acid fractionated IgG antivenom for the treatment of taipan (Oxyuranus scutellatus) envneoming in Papua New Guinea
  • artículo original
2011

No disponible

Immune Response Towards Snake Venoms
  • artículo original
2011
Snake Venomics of African Spitting Cobras: Toxin Composition and Assessment of Congeneric Cross-Reactivity of the Pan-African EchiTAb-Plus-ICP Antivenom by Antivenomics and Neutralization Approaches
  • artículo original
2011
Método para la producción de formulaciones inyectables de productos proteicos hemoderivados y productos obtenidos utilizando dicho método
  • patente
2011
Preclinical assessment of the neutralizing capacity of antivenoms produced in six Latin American countries against medically-relevant Bothrops snake venoms
  • artículo original
2010

No disponible

Antivenomic Assessment of the Immunological Reactivity of EchiTAb-Plus-ICP, an Antivenom for the Treatment of Snakebite Envenoming in Sub-Saharan Africa
  • artículo original
2010

No disponible

Neutralization of Bothrops mattogrossensis snake venom from Bolivia: Experimental evaluation of llama and donkey antivenoms produced by caprylic acid precipitation
  • artículo original
2010

No disponible

Study of the design and analytical properties of the lethality neutralization assay used to estimate antivenom potency against Bothrops asper snake venom
  • artículo original
2010

No disponible

Preclinical assessment of the efficacy of a new antivenom (EchiTAb-Plus-ICP) for the treatment of viper envenoming in sub-Saharan Africa
  • artículo original
2010

No disponible

Intravenous administration of equine-derived whole IgG antivenom does not induce early adverse reactions in non-envenomed horses and cows
  • artículo original
2010

No disponible

Snake venomics and antivenomics of Bothrops colombiensis, a medically important pitviper of the Bothrops atrox-asper complex endemic to Venezuela: Contributing to its taxonomy and snakebite management
  • artículo original
2009

No disponible

Stability of equine IgG antivenoms obtained by caprylic acid precipitation: Towards a liquid formulation stable at tropical room temperature
  • artículo original
2009

No disponible

Human heterophilic antibodies against equine immunoglobulins: assessment of their role in the early adverse reactions to antivenom administration
  • artículo original
2008
Factors associated with adverse reactions induced by caprylic acid-fractionated whole IgG preparations: comparison between horse, sheep and camel IgGs
  • artículo original
2005